Assistant Professor
School of Medicine
Research Scientist
Drumm Lab
Department of Genetics and Genome Sciences
School of Medicine
Research Information
Research Interests
My research revolves around two main topics: excessive inflammation observed in the lungs of cystic fibrosis (CF) patients and the malnutrition and malabsorption seen in these patients.
Publications
- Gupta S, Heacock M, Perez A, and Davis PB. Antibodies to the polymeric immunoglobulin receptor with different binding and trafficking Patterns. Am. J. Respir. Cell. Mol. Biol. 33(4):363-370, 2005.
- Perez A, Issler AC, Cotton CU, Kelley TJ, Verkman AS, and Davis PB. CFTR inhibition mimics the cystic fibrosis inflammatory profile. Am. J. Physiol. Lung Cell. Mol. Physiol. 292(2):L383-L395, 2007
- Perez A, van Heeckeren AM, Nichols D, Gupta S, Eastman JF, and Davis PB. Peroxisome proliferators-activated receptor gamma in cystic fibrosis lung epithelium. Am. J. Physiol. Lung Cell. Mol. Physiol. 295(2):L303-L313, 2008. PMC2519842.
- Perez A, and Davis PB. Gene profile changes after pseudomonas aeruginosa exposure in immortalized airway epithelial cells. JSFG 5:179-194, 2004.
- Bryan R, Kube D, Perez A, Davis PB, and Prince A. Overproduction of the CFTR R domain leads to increased levels of asialoGM1 and increased Pseudomonas aeruginosa binding by epithelial cells. Am J Respir Cell Mol Biol. 19(2):269-277, 1998.
- Kube D, Adams L, Perez A, and Davis PB. Terminal sialylation is altered in airway cells with impaired CFTR-mediated chloride transport. Am. J. Physiol. Lung Cell. Mol. Physiol. 280(3):L482-L492, 2001.