2025 TGS Conference

Thank you to everyone who attended the inaugural Translational Glial Sciences Conference. We were delighted to welcome a full house to our first event as the Institute for Glial Sciences, and we are grateful tto welcome so many new glial scientists into our growing community.

We look forward to building on this momentum as we plan for next year’s conference. Stay tuned for updates on our 2026 conference!

A collage of people attending the first ever Glial conference held by IGS

 

The Institute for Glial Sciences was pleased to host the inaugural Translational Glial Sciences Conference on November 4, 2025 at the Sheila and Eric Samson Pavilion of the Health Education Campus of Case Western Reserve University and Cleveland Clinic. The conference brought together scientists at the forefront of glial sciences to share their latest findings on the impact of glia in a range of diseases, along with emerging opportunities to target glia for therapeutic benefit.

The event also marked the launch of the Institute for Glial Sciences, the newest institute at Case Western Reserve University, established to illuminate the hidden role of glia in disease and advance the era of glial medicines.

 


Four featured participants in the 2025 Translational Glial Sciences Conference are shown with circular headshots and text. Top left: Lorenz Studer, MD of Memorial Sloan Kettering Cancer Center, labeled as Keynote Speaker. Top right: Bruce Trapp, PhD of Cleveland Clinic, labeled as Plenary Speaker. Bottom left: Paul J. Tesar, PhD of the Institute for Glial Sciences, labeled as Chair. Bottom right: Raeka Aiyar, PhD of the Institute for Glial Sciences, also labeled as Chair.

Agenda

 9:30 Online Registration closes

11:30 Check in and Lunch 

12:30 Conference begins

           Master of Ceremonies: Raeka Aiyar, PhD | Institute for Glial Sciences, Case Western Reserve University 

           Welcome by Dean Stanton L. Gerson, MD, Case Western Reserve University School of Medicine

12:40 Paul Tesar, PhD | Institute for Glial Sciences, Case Western Reserve University

The IGS Blueprint for Glial Medicines: Lessons from Oligodendrocytes

1:10 Bruce Trapp, PhD | Cleveland Clinic

Plenary Lecture: Glia Cells in the Pathogenesis of Multiple Sclerosis

1:40 Tracy Young-Pearse, PhD | Harvard Medical School, Brigham and Women’s Hospital

Moving beyond amyloid and tau to capture the biological heterogeneity of Alzheimer’s disease using human IPSC models 

2:05 Break

2:30 Marissa Scavuzzo, PhD | Institute for Glial Sciences, Case Western Reserve University

Understanding glia in the brain inside your gut

2:45 Allison Bradbury, PhD | Nationwide Children’s Hospital

Development of genetic therapies for inherited pediatric leukodystrophies

3:10 Tyler Miller, MD, PhD | Institute for Glial Sciences, Case Western Reserve University

Redefining and targeting the immune microenvironment in glial diseases

3:25 Dimitry Ofengeim, PhD | Sanofi

Key drivers of disease progression in multiple sclerosis

3:50 Benjamin Clayton, PhD | Institute for Glial Sciences, Case Western Reserve University

Modulating reactive glia to promote neuroprotection

4:05 Break

4:30 Lorenz Studer, MD | Memorial Sloan Kettering Cancer Center

Keynote Address

5:00 Panel discussion: The Promise of Glial Medicines

Panelists: Richard Ransohoff, MD | Paul Tesar, PhD | Tracy Young-Pearse, PhD | Lorenz Studer, MD | Moderator: Raeka Aiyar, PhD

5:45 Conclusion