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Health + Wellness

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On FDA panel, CWRU professor endorses new ketamine-related depression medication
As part of panel of experts convened by the U.S Food and Drug Administration (FDA), Case Western Reserve University professor Lee Hoffer voted last week to recommend a new nasal spray for treatment-resistant depression that some are touting as the most significant development in a generation for…
Preventing “Cell Wall Remodeling” May Hold Key to Defeating Intransigent Superbugs in Cystic Fibrosis, Other Diseases
B. multivorans is a notorious pathogen that can cause infections such as pneumonia in immune-compromised individuals with underlying lung diseases, including cystic fibrosis. This pathogen can also cause rapid clinical deterioration in patients, including blood stream infections, which can lead to…
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Can Heart Failure Be Prevented?
It’s important to know that despite its name, “heart failure” does not mean your heart has failed or stopped working. So what does it really mean? The term actually describes a medical condition in which the heart isn’t pumping enough blood to meet the body’s needs for blood and oxygen.  You may…
KL2 Scholar Alumna Receives Funding to Identify Interventions for Intimate Partner Violence
CTSC KL2 Scholar alumna and associate professor of psychiatry at the CWRU School of Medicine, Gunnur Karakurt, PhD has been awarded a four-year, $1.3 million grant from the National Institutes of Health to identify effective treatments for intimate partner violence (IPV), and to develop a…
Case Western Reserve Researcher Awarded $1.3 Million to Develop Decision-Making Tool for Treating Intimate Partner Violence
Case Western Reserve University School of Medicine’s Gunnur Karakurt, PhD has been awarded a four-year, $1.3 million grant from the National Institutes of Health to identify effective treatments for intimate partner violence (IPV), and to develop a decision-making tool for care providers. The…
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Case Western Reserve/University Hospitals researcher part of elite trans-Atlantic network to study “molecular switch” that contributes to heart disease
Paris-based foundation supports effort to potentially “turn off” vascular problems Transcription factors are proteins that determine whether specific genes are transcribed or not by binding to DNA. In other words, they help turn genes "on" or "off." One such transcription factor, Kruppel-like…
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Database funded to help researchers understand the effect of bipolar disorder throughout adult life span
Research aims to assist patients and caregivers’ plan care choices Not much is known about how bipolar disorder (BD) affects people throughout their lives. Do women and men differ in the severity of their symptoms? Does a person’s age when a bipolar diagnosis is made have any bearing on how severe…
Blood Cells Could Hold Master Clock Behind Aging
Blood cells could hold the key to aging, according to new research out of Case Western Reserve University School of Medicine. In a study published in Aging Cell, researchers found human blood cells have an intrinsic clock that remains steady even after transplant. The researchers say the clock…
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New images show serotonin activating its receptor for first time
High-tech microscope reveals receptor in action, with focus on drug development Serotonin (3A) receptors are common drug targets in the treatment of pain, gastrointestinal dysfunctions, and mood disorders, yet little is known about their three-dimensional structure. Details about serotonin receptor…
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R for Quantitative Health Sciences: An Interview with Jarrod Dalton
Jarrod Dalton, PhD is a CTSC KL2 Scholar alum and an assistant staff scientist in the Department of Quantitative Health Sciences and an assistant professor of medicine in the Cleveland Clinic Lerner College of Medicine at Case Western Reserve University in Cleveland, Ohio. This interview focuses on…