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Computer program finds new uses for old drugs
Researchers repurpose pain meds to kill cancer cells Researchers at the Case Comprehensive Cancer Center (CCCC) at Case Western Reserve University have helped develop a computer program to find new indications for old drugs. The computer program, called DrugPredict, matches existing data about FDA-...
Researchers Receive $2.8 Million to Repurpose FDA-approved Drugs to Treat Alzheimer’s Disease
Researchers from Case Western Reserve University School of Medicine and collaborators have received a five-year, $2.8 million grant from the National Institute on Aging to identify FDA-approved medications that could be repurposed to treat Alzheimer’s disease. The award enables the researchers to de...
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New study offers added hope for patients awaiting corneal transplants
Donor tissue can be stored for 11 days before transplantation—four days longer than current convention New national research led by Jonathan Lass of Case Western Reserve University School of Medicine has found that corneal donor tissue can be safely stored for 11 days before transplantation surgery ...
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Happy New Year
The holiday season is over … the wrapping paper that was strewn about the room has been collected and discarded; the lights unstrung and put away, the needles from the greens swept up. The New Year is upon us. It’s 2018. We are now in our 175th anniversary year. It will be August before we commemor...
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Alevca Ocular gains CWRU Technology Transfer licenses to develop and commercialize novel ophthalmological drugs
Alevca Ocular LLC has secured licenses from Case Western Reserve University’s Technology Transfer Office (TTO) to exclusively use university-funded research to develop and commercialize novel ophthalmological drugs. Alevca Ocular, an early-stage company based in San Clemente, California, has licens...
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Researchers receive Department of Defense grant for implantable muscle stimulator
Device aims to benefit patients with spinal cord injuries, including combat veterans A team of researchers led by Kath Bogie, a biomedical engineer and associate professor of orthopaedics and biomedical engineering at Case Western Reserve University School of Medicine, has received a $1.8 million, t...
Zooming in on Protein to Prevent Kidney Stones
Researchers have applied Nobel prize-winning microscope technology to uncover an ion channel structure that could lead to new treatments for kidney stones. In a recent study published in Nature Structural and Molecular Biology, researchers revealed atomic-level details of the protein that serves as ...
Fish Use Deafness Gene to Sense Water Motion
Fish sense water motion the same way humans sense sound, according to new research out of Case Western Reserve University School of Medicine. Researchers discovered a gene also found in humans helps zebrafish convert water motion into electrical impulses that are sent to the brain for perception. Th...
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Case Western Reserve research advance may prevent a form of hereditary hearing loss
Four-fold improvement in hearing for a mouse model of deafness A research advance co-led by Case Western Reserve University School of Medicine’s Kumar Alagramam may stop the progression of hearing loss and lead to significant preservation of hearing in people with Usher syndrome type III, a form of ...
Two Studies Find Stress Reprograms Cells
In a pair of publications, researchers have shown how cells adapt to stressors—like water loss—by reprogramming their internal signaling networks. The studies describe previously unknown mechanisms that cells use to send signals between cellular machinery and avoid cell death. According to the autho...