Health + Wellness

A person’s DNA sequence can provide a lot of information about how genes are turned on and off, but new research out of Case Western Reserve University School of Medicine suggests the 3-D structure DNA forms as it crams into cells may provide an additional layer of gene control. As long strands of D...

In a World View opinion column published in Nature, a Case Western Reserve University School of Medicine researcher calls for animal-human embryo research to proceed – but only with strong animal protections in place. So-called “chimera” research raises the hope of producing human organs in genetica...

A new scientific study reveals one way to stop proteins from triggering an energy failure inside nerve cells during Huntington’s disease. Huntington’s disease is an inherited genetic disorder caused by mutations in the gene that encodes huntingtin protein. Approximately 30,000 Americans have mutant ...

Jonathan Karn, PhD, Reinberger Professor of Molecular Biology and chairman of the Department of Molecular Biology and Microbiology at Case Western Reserve University School of Medicine, and director of the Case Center for AIDS Research, has been awarded the 2016 Drexel Prize in Translational Medicin...

Insoo Hyun, PhD, associate professor of bioethics at the School of Medicine of Case Western Reserve University, has proposed a framework for addressing ethical questions surrounding potentially revolutionary research on part-human, part-animal embryos, which can be produced when human stem cells are...

Goal: Investigate the role of intestinal innate immunity in Crohn’s disease Fabio Cominelli, a professor in the departments of Medicine and Pathology at Case Western Reserve University School of Medicine and director of the school’s Digestive Health Research Institute, has received a $9.7 million, f...

Invited commentary by Drs. Paula Silverman and Cheryl Thompson A recent study by Jones et al. in The British Journal of Cancer (BJC)(Jones ME. Br J Cancer. 2016 Aug 23) estimated an almost 3 fold (2.74 times) increase risk of breast cancer among post-menopausal women who used combination estrogen ...

15 gene mutations lead to higher recurrence and metastasis; genes may contribute to lower survival rates seen in African-Americans Case Comprehensive Cancer Center researchers, a research collaboration which includes University Hospitals Seidman Cancer Center and Case Western Reserve University, wh...

Case Comprehensive Cancer Center researchers identify several structurally abnormal genes in esophageal adenocarcinoma in first ever genome-wide search Despite years of research, cellular mechanisms contributing to cancers like esophageal adenocarcinoma have remained elusive. What has puzzled resea...

This past week attended the national meeting of the Association of American Cancer Institutes (AACI) in Chicago. It was an excellent meeting of cancer center directors and administrators that included discussion of implementation of genomic tumor boards, use of molecular testing in clinical practic...