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Health + Wellness

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Researchers Find Gene Mutations Lead to More Aggressive Colon Cancer in African-Americans
15 gene mutations lead to higher recurrence and metastasis; genes may contribute to lower survival rates seen in African-Americans Case Comprehensive Cancer Center researchers, a research collaboration which includes University Hospitals Seidman Cancer Center and Case Western Reserve University,…
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Fused Genes Found in Esophageal Cancer Cells Offer New Clues on Disease Mechanisms
Case Comprehensive Cancer Center researchers identify several structurally abnormal genes in esophageal adenocarcinoma in first ever genome-wide search Despite years of research, cellular mechanisms contributing to cancers like esophageal adenocarcinoma have remained elusive. What has puzzled…
AACI national meeting, presentation by Doug Lowy, Acting Director of NCI
This past week attended the national meeting of the Association of American Cancer Institutes (AACI) in Chicago. It was an excellent meeting of cancer center directors and administrators that included discussion of implementation of genomic tumor boards, use of molecular testing in clinical…
Fluoride Consumption Linked to Diabetes Using Mathematical Models
Water fluoridation prevents dental cavities, which are a costly public health concern. But despite the benefits supplemental water fluoridation remains a controversial subject. Some indicate it may cause long term health problems, but studies reporting side effects have been minimal or…
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Study reveals recording selfies while brushing teeth can improve oral health
Recording smart phone video “selfies” of tooth-brushing can help people learn to improve their oral health care techniques, according to a new study. While most people have the motivation, innate ability and desire to brush their teeth properly, they often do not because of they use an improper…
Researchers Restore Drug Sensitivity in Breast Cancer Tumors
Findings confirmed in patient biopsies and laboratory models A team of Case Comprehensive Cancer Center researchers has uncovered one way certain tumors resist vital medication. In the study published in Oncotarget (Merry CR. Oncotarget. 2016 Jul 16), the researchers studied tumor biopsies…
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Researchers lead team in discovering possible approach to slow growth of certain colon cancers
The body’s most common amino acid just may provide a path to slow the growth of certain colon cancers. Researchers at the Case Western Reserve School of Medicine led an international team in demonstrating that depriving certain kinds of colorectal cancer cells of glutamine suppresses the ability…
VeloSano 3
7 am Saturday morning saw the 100 and 200+ mile Velosano bikers head off with the cheers of friends and leaders - I saw Brian Bolwell safely behind the roadside barrier smiling, arms raised. The day was perfect for riders - cool, with a short thunderstorm on the way in and a relaxing scenic route…
Scientists Keep a Molecule from Moving Inside Nerve Cells to Prevent Cell Death
Amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease) is a progressive disorder that devastates motor nerve cells. People diagnosed with ALS slowly lose the ability to control muscle movement, and are ultimately unable to speak, eat, move, or breathe. The cellular mechanisms behind ALS are…
Cancer Moonshot Breakfast Panel
Message from the Associate Director: Brian Bolwell, MD Thomas Donohue, President and CEO, US Chamber of Commerce, hosted a Cancer Moonshot Breakfast Panel in downtown Cleveland last Wednesday. I participated in the panel, along with Toby Cosgrove, MD, President and CEO of Cleveland Clinic, Louis…