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Health + Wellness

Robust immune biomarker predicting survival in HPV-positive head and neck squamous cell carcinoma identified
From University Hospitals: Quintin Pan, PhD and colleagues at University Hospitals (UH) Seidman Cancer Center have identified biomarker immunoglobulin J polypeptide (IGJ), uniquely expressed in plasma cells, predicts early disease-specific mortality among HPV-positive patients with HNSCC. The team p...
Colorectal cancer relapse predicted by immune cell infiltration
From Cleveland Clinic Lerner Research Institute: A research team led by Stephanie Schmit, PhD, MPH, Genomic Medicine Institute, has found that immune cell infiltration of colorectal cancer (CRC) tumors can predict disease relapse in patients who undergo surgery with curative intent. Published in Onc...
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A team effort
Journey to multi-million dollar Amgen acquisition required curiosity, collaboration and commercial expertise Twenty years after starting a cancer fellowship at the National Institutes of Health (NIH), Sanford “Sandy” Markowitz published a groundbreaking study regarding the role of a gene called 15-...
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Vaccines and epidemics: Lessons from history
By Jonathan Sadowsky, the Castele Professor of Medical History I often start a new class by asking why we should study history. I don’t allow the cliché “History repeats itself,” without specific examples. The history of epidemics provides some: racist scapegoating, denialism, resistance to public...
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New formulation of existing medicines prove highly effective against drug-resistant fungus
Spread of Candida auris on skin—a source of deadly infections—can be effectively stopped, according to new Case Western Reserve University research A team of researchers from Case Western Reserve University has discovered a formulation of existing medicines that can significantly reduce the presenc...
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Sharifi honored with AACR achievement award for discoveries in cancer research
The Case Comprehensive Cancer Center extends congratulations to Cleveland Clinic's Nima Sharifi, MD, as he has been selected as the 2021 recipient of the American Association for Cancer Research (AACR) Waun Ki Hong Award for Outstanding Achievement in Translational and Clinical Cancer Research. In ...
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Mt. Sinai Health Care Foundation awards $1 million grant to Case Western Reserve University School of Medicine
The Mt. Sinai Health Care Foundation—continuing Mt. Sinai Medical Center’s century-old tradition of caring for Northeast Ohio—has expanded its commitment to the region through a $1 million challenge grant to the Case Western Reserve University School of Medicine. With this grant, the Mt. Sinai Healt...
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Case Western Reserve University biotech startup Rodeo Therapeutics Corp. sold to Amgen Inc.
Deal worth $55M, plus potential milestones of up to $666M Rodeo Therapeutics Corp., a drug-development startup founded by two leading researchers from Case Western Reserve University School of Medicine and a third scientific partner, has been sold to Amgen Inc., a publicly traded international biop...
Student Spotlight: Michelle Lee
Fourth-year student Michelle Lee decided somewhat recently, during her last years as an undergraduate at the University of California, Berkeley, to study medicine. “I had volunteered with children and was studying to be a teacher,” Lee explained. “That changed after becoming involved in a program ...
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Nursing’s Heather K. Hardin explores trust in health care professionals
When nurse researcher Heather K. Hardin was working as a Women, Infants and Children (WIC) nurse serving a population of mostly low-income mothers, she kept hearing the same question. “Moms would tell me, ‘I don’t trust so and so,’ or ‘Can I come back and talk to you about this?’ I was a PhD studen...