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Health + Wellness

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Scientists design 3D model of molecule key to halting tumor growth
Research into stopping tumor growth was recently featured in BBC Science Focus Magazine as one of the world's "20 moments in 2020 to be excited about." A compound that activates an enzyme capable of suppressing tumors was discovered by a cross-institutional team from the University of Michigan and C...
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First glioblastoma patient dosed with Phase 2 trial at UH Seidman Cancer Center testing PVSRIPO plus Keytruda
Glioblastoma, recognized as the most aggressive primary brain cancer in adults is also known to be among the most immunosuppressive of tumors. A Phase 2 clinical trial of PVSRIPO, a revolutionary viral immunotherapy for cancer treatment, in combination with Keytruda (pembrolizumab) is underway acros...
Potential new target for treating chemotherapy-associated kidney damage
From Cleveland Clinic Lerner Research Institute: Standard-of-care treatment for many cancers includes chemotherapy drug cisplatin which prevents the spread of cancer cells by interrupting DNA replication and damaging the genetic material in rapidly dividing tumor cells. Unfortunately, the drug can c...
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Case Western Reserve, Cleveland Department of Public Health form partnership to battle COVID-19, other infectious diseases
The Cleveland Department of Public Health (CDPH) and Case Western Reserve University, through its Master of Public Health Program (MPH) at the School of Medicine, have forged a partnership to respond to the COVID-19 pandemic. The new partnership will help ensure high-quality COVID-19 epidemiology i...
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COVID-19: bioethical issues raised by the pandemic
A Q&A with Case Western Reserve University Professor Mark Aulisio Mark Aulisio, the Susan E. Watson Professor and chair of the Department of Bioethics at Case Western Reserve University School of Medicine, weighed in on bioethical issues that have arisen as a result of the COVID-19 pandemic in thi...
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CWRU Researchers Can Now Apply for Access to the N3C Data Enclave
Case Western Reserve University has signed an institutional Data Use Agreement (DUA) with the National Center for Advancing Translational Sciences (NCATS). Through this master agreement, CWRU faculty members (who receive their compensation directly from CWRU) are eligible to submit Data Use Requests...
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Uganda-CWRU Research Collaboration site awarded 10-year grant renewal for tuberculosis research
Case Western Reserve University (CWRU) and the Uganda-CWRU Research Collaboration team were recently awarded a 10-year, $1.8 million per year, contract renewal from the Tuberculosis Trials Consortium (TBTC), part of the Center for Disease Control and Prevention (CDC). The TBTC is an international co...
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Studying system biology at the atomic level
Outlet: Nature Methods Published: January 6, 2021 A ‘Build and Retrieve’ methodology to simultaneously solve cryo-EM structures of membrane proteins Authors: Edward Yu, professor of pharmacology at CWRU School of Medicine and researchers from the University of Oxford, Oxford, UK ...