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Health + Wellness

Colorectal cancer research funded by the National Cancer Institute investigates new potential immunotherapy targets
A team of researchers from CWRU and UH is investigating the role of Erbb3 in the development of colorectal cancer. To put it simply, says lead investigator Zhenghe John Wang, PhD, the team is attempting to discover the pathways that can switch the cold tumors to hot tumors, and activate immune…
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Study Shows Machine Learning’s Potential to Predict Cancer Therapy-Related Cardiac Risk
From Cleveland Clinic Lerner Research Institute: Machine learning-based approaches to risk assessment can be highly effective in predicting various types of cardiac dysfunction among cancer survivors who have received cardiotoxic cancer therapies, according to a new retrospective longitudinal study…
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Why rape victims are so often left to solve their own cases
Case Western Reserve University researchers examine how the ‘bureaucratic burden’ of taking rapists off the streets can impede justice—often for society’s most vulnerable Samuel Little, the man the FBI called the nation’s most prolific serial killer, admitted last year to raping and killing 93…
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Case Western Reserve researchers uncover biochemical rules between RNA-protein interactions and expression of thousands of genes
Work has potential implications for new therapies to treat cancer and neurodegenerative disorders A team of Case Western Reserve University researchers has found a way to measure key characteristics of proteins that bind to RNA in cells—a discovery that could improve our understanding of how gene…
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Case Western Reserve University-led team finds that people with dementia at higher risk for COVID-19
Research documents more cases, hospitalizations and deaths, with odds of both infection and worse outcomes higher for African Americans A study led by Case Western Reserve University researchers found that patients with dementia were at a significantly increased risk for COVID-19—and the risk was…
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Scientists design 3D model of molecule key to halting tumor growth
Research into stopping tumor growth was recently featured in BBC Science Focus Magazine as one of the world's "20 moments in 2020 to be excited about." A compound that activates an enzyme capable of suppressing tumors was discovered by a cross-institutional team from the University of Michigan and…
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First glioblastoma patient dosed with Phase 2 trial at UH Seidman Cancer Center testing PVSRIPO plus Keytruda
Glioblastoma, recognized as the most aggressive primary brain cancer in adults is also known to be among the most immunosuppressive of tumors. A Phase 2 clinical trial of PVSRIPO, a revolutionary viral immunotherapy for cancer treatment, in combination with Keytruda (pembrolizumab) is underway…
Potential new target for treating chemotherapy-associated kidney damage
From Cleveland Clinic Lerner Research Institute: Standard-of-care treatment for many cancers includes chemotherapy drug cisplatin which prevents the spread of cancer cells by interrupting DNA replication and damaging the genetic material in rapidly dividing tumor cells. Unfortunately, the drug can…
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Case Western Reserve, Cleveland Department of Public Health form partnership to battle COVID-19, other infectious diseases
The Cleveland Department of Public Health (CDPH) and Case Western Reserve University, through its Master of Public Health Program (MPH) at the School of Medicine, have forged a partnership to respond to the COVID-19 pandemic. The new partnership will help ensure high-quality COVID-19 epidemiology…