Research Impact

Researchers find new hints that could explain how the disease spreads in human brains Case Western Reserve University researchers studying human prions—misfolded proteins that cause lethal and incurable diseases—have, for the first time, identified surface features responsible for the replication o...

Second ‘Cichlid’ fish species—native to Mexico—now threatening waters of southern United States, invading waterways in Louisiana A Case Western Reserve University scientist has played the lead role in identifying an invasive species related to one already threatening other fish in the waters of the...

Follow-up data from the landmark SPRINT study of the effect of high blood-pressure on cardiovascular disease have confirmed that aggressive blood-pressure management—lowering systolic blood-pressure to less than 120 mm Hg—dramatically reduces the risk of heart disease, stroke and death from these di...

Case Western Reserve University scientists show that artificial intelligence tools can work effectively for different locations, populations For artificial intelligence (AI) to realize its full potential to benefit cancer patients, researchers will have to prove that their machine-learning successe...

Findings provide clues to how toxic proteins clump and spread Scientists at Case Western Reserve University School of Medicine have determined the structure of protein “fibrils” linked to Lou Gehrig’s disease and other neurodegenerative disorders—findings that provide clues to how toxic proteins ...

Case Western Reserve University-developed imaging agent for MRI prostate cancer detection gets FDA approval for safety trials, set to begin this month in Columbus The U.S. Food and Drug Administration has approved human clinical trials to test the safety of cancer-detection technology developed at ...

Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with Down syndrome (DS), researchers from Case Western Reserve University, Cleveland Clinic, University Hospitals and other institutions detected subtle differences in the structure and function of the hippocampus—a ...

Researchers collaborate on genetic study of SARS-CoV-2 mutations Since the start of the COVID-19 pandemic, mutations of SARS-CoV-2—the virus that causes COVID-19—have spread to the U.S. and a host of other countries worldwide. Recent studies suggest that current COVID-19 variants are up to 70% more...

Novel small molecule technology reverses life-threatening opioid-induced respiratory depression without diminishing pain relief Case Western Reserve University and Atelerix Life Sciences Inc., a Charlottesville, Virginia-based biotechnology company, have signed a two-year option to license a novel ...

An international team of bioethicists and scientists, led by a researcher at Case Western Reserve University, contends it may be justified to go beyond the standing 14-day limit that restricts how long researchers can study human embryos in a dish. Going beyond this policy limit could lead to potent...