Research Impact

Follow-up data from the landmark SPRINT study of the effect of high blood-pressure on cardiovascular disease have confirmed that aggressive blood-pressure management—lowering systolic blood-pressure to less than 120 mm Hg—dramatically reduces the risk of heart disease, stroke and death from these…

Case Western Reserve University scientists show that artificial intelligence tools can work effectively for different locations, populations For artificial intelligence (AI) to realize its full potential to benefit cancer patients, researchers will have to prove that their machine-learning…

Findings provide clues to how toxic proteins clump and spread Scientists at Case Western Reserve University School of Medicine have determined the structure of protein “fibrils” linked to Lou Gehrig’s disease and other neurodegenerative disorders—findings that provide clues to how toxic proteins…

Case Western Reserve University-developed imaging agent for MRI prostate cancer detection gets FDA approval for safety trials, set to begin this month in Columbus The U.S. Food and Drug Administration has approved human clinical trials to test the safety of cancer-detection technology developed at…

Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with Down syndrome (DS), researchers from Case Western Reserve University, Cleveland Clinic, University Hospitals and other institutions detected subtle differences in the structure and function of the hippocampus—a…

Researchers collaborate on genetic study of SARS-CoV-2 mutations Since the start of the COVID-19 pandemic, mutations of SARS-CoV-2—the virus that causes COVID-19—have spread to the U.S. and a host of other countries worldwide. Recent studies suggest that current COVID-19 variants are up to 70%…

Novel small molecule technology reverses life-threatening opioid-induced respiratory depression without diminishing pain relief Case Western Reserve University and Atelerix Life Sciences Inc., a Charlottesville, Virginia-based biotechnology company, have signed a two-year option to license a novel…

An international team of bioethicists and scientists, led by a researcher at Case Western Reserve University, contends it may be justified to go beyond the standing 14-day limit that restricts how long researchers can study human embryos in a dish. Going beyond this policy limit could lead to…

One of just 12 researchers nationally chosen for biomedical study to potentially benefit children Yolanda Fortenberry Yolanda Fortenberry, an associate professor of biology at Case Western Reserve University studying possible therapies for debilitating sickle cell disease, is one of just 12…

Case Western Reserve-led team among 38 from 16 countries selected to compete for $10 million prize A team led by Case Western Reserve University biomedical engineer Dustin Tyler has made it a step closer to the finals in a global competition to develop an “Avatar System that will transport a…