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Research Impact

ECRISPR
CRISPR: More than just for gene editing?
Case Western Reserve researcher finds new use for revolutionary gene-splicing tool; electrochemical platform could lead to blood test for HPV, parvo or others The gene-editing tool CRISPR has been heralded as a scientific miracle destined to eradicate diseases from sickle-cell anemia to cancer,…
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Case Western Reserve researchers to lead Northeast Ohio initiative to prevent, detect and treat lung cancer in underserved communities
Supported with three-year, $2.75M grant from Bristol-Myers Squibb Foundation With a $2.75 million, three-year grant from the Bristol-Myers Squibb (BMS) Foundation, researchers from Case Western Reserve University will lead a community-wide initiative to create and apply innovative methods to…
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Clinical trials planned for brain tumor ‘GPS’ maps
Case Western Reserve University School of Medicine researcher, Cleveland Clinic neurosurgeon collaborate on three-year project, aided by $600,000 grant A GPS map to guide neural navigation devices developed by a Case Western Reserve University cancer researcher has shown 90% accuracy in…
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Case Western Reserve social sciences researchers develop new tool to assess exposure to childhood violence, trauma
Designed in response to high exposure rates, new screening measure expected to be implemented nationally One in five children in Cuyahoga County, Ohio, are either exposed to, or are victims of, violence and trauma, according to a new study from the Jack, Joseph and Morton Mandel School of Applied…
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Case Western Reserve University researchers discover critical link to controlling inflammation in Crohn’s disease
Findings could support first clinical trial Investigators at the Case Western Reserve University School of Medicine discovered that blocking interleukin-1α (IL1α), a protein that controls inflammation in the gut, markedly decreases the severity of intestinal inflammation in a mouse model of…
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New hope for osteoporosis, more durable airplane wings
Case Western Reserve researcher on team that prints 3D model to prove importance of ‘transverse struts’ to long-term structure life New bone-structure research from scientists at Case Western Reserve, Cornell and Purdue universities could give new hope to patients suffering from osteoporosis—and…
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Training middle-school educators to identify suicide warning signs
Case Western Reserve University research examines virtual role-playing to address student mental health, suicide Aside from car crashes, suicide is now the second-leading cause of death among young people in the United States, according to the Centers for Disease Control and Prevention. In Ohio…
immunotherapy
Using artificial intelligence to determine whether immunotherapy is working
Case Western Reserve researchers use AI with routine CT scans to predict how well lung cancer patients will respond to expensive treatment based off changes in texture patterns inside and outside the tumor Scientists from the Case Western Reserve University digital imaging lab, already pioneering…
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New study explores the link between obesity and gum disease
CWRU School of Dental Medicine research suggests treating one may impact the other Obesity and gum (periodontal) disease are among the most common non-communicable diseases in the United States—and studies show these chronic conditions may be related. This new study explores the effect of obesity…
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New research from Case Western Reserve University identifies neurodevelopment-related gene deficiency
Findings may lead to clues for possible treatments for autism spectrum disorders and schizophrenia Researchers at the Case Western Reserve University School of Medicine have identified that a gene critical to clearing up unnecessary proteins plays a role in brain development and contributes to the…