Science + Tech

human Estrogen Receptor alpha Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually develop drug resistance, leaving doctors desperate for…

Ahmad Khalil, PhD Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding genes also contribute to the development and spreading…

Targeting longnNoncoding RNAs may offer gains compared to conventional approaches Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding…

A team of investigators led by Nima Sharifi, MD, GU Malignancies Program Leader, Case Comprehensive Cancer Center, and Kendrick Family Chair for Prostate Cancer Research at Cleveland Clinic Lerner Research Institute, have been awarded the 2018 Mizel Family Foundation PCF VAlor Challenge Award for…

The Case Comprehensive Cancer Center (Case CCC) has been awarded a five-year, $1.6 million grant from the National Cancer Institute to fund a newly created program that will engage undergraduate scholars in cancer research. The Cancer-focused Summer Undergraduate Research program (CanSUR) will be…

The Office of Cancer Disparities Research of the Case Comprehensive Cancer Center (Case CCC)  has made pilot award selections following a recent RFA. The awards are an effort to stimulate research designed to both improve understanding of contributing factors to cancer disparities as well as…

Researchers from Case Western Reserve University School of Medicine have shown that a single “cocktail” of three pill-based anti-parasite medications is significantly more effective at killing microscopic larval worms in people diagnosed with lymphatic filariasis, commonly known as elephantiasis,…

Non-contrast based technique may benefit patients with peripheral arterial disease Case Western Reserve University School of Medicine has received a three-year, $1,118,556 grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to investigate a new imaging…

Mukesh Jain, MD, and colleagues have been awarded a five-year, $6M grant from the Paris-based Fondation Leducq to conduct a thorough analysis of the pivotal role of KLF2 in vascular-related functions and disorders. The team’s grant was one of five awarded globally and aims to improve knowledge and…

Lin Mei, MD, PhD, joins Case Western Reserve University School of Medicine as professor, chair of the Department of Neurosciences, and director of the Cleveland Brain Health Initiative. Mei comes to the medical school following 13 highly productive years at Medical College of Georgia at Augusta…