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Science + Tech

5-Year Follow Up Results of SWOG Prevention of Early Menopause Study (POEMS) Clinical Trial Show Means of Improved QOL for Patients
An international team of researchers and clinicians participated in the SWOG Cancer Research Network's POEMS clinical trial. While initial findings released in 2014 were positive, the follow-up results 5 years later are groundbreaking.  The trial included patients with hormone-receptor negative…
Director's Message: National Cancer Policy Forum: Computational Tools for Diagnosis and Decision-making
"Clinical Applications of Computational Methods in Precision Oncology" was the topic of the National Cancer Policy Forum at the National Academy of Medicine on October 29-30, 2018 [View workshop speakers and agenda]. I would like to summarize key observations, and provide you with an update on the…
Single Protein Controls Thousands of Genes Essential for Sperm Development
Tissue from a mouse that has a functional Dazl gene, with fluorescent-labeled germ cells (left), and tissue from a mouse lacking the Dazl gene (right). A single protein regulates a battery of key genes inside developing sperm, according to a new study out of Case Western Reserve…
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Understanding the neurological code behind how flies fly
Case Western Reserve scientists study acrobatic maneuvers of common flesh flies, offer first proofs of 70-year-old theory on nervous system controlling body rotations A common flesh fly takes off and maneuvers effortlessly, her head and body steadied by a hidden, minuscule gyroscope-like structure…
Director's Message: 10-Year Outlook for Cancer Centers
At the October 1-2 Association of American Cancer Institutes (AACI) meeting in Chicago, there were a number of interesting sessions covering global cancer research and care, physician burnout (high in oncology), use of big data in cancer care and research, and the explosion in breast cancer…
NHLBI grant to fund research toward prevention of cancer-related venous thromboembolism
A five-year grant from the National Heart, Lung, and Blood Institute of $4.7 million is funding research by two Case Comprehensive Cancer Center members. "About 20% of [patients with cancer] develop blood clots, which can cause stroke, hospitalization, and delays in treatment. In fact,…
Case Western Reserve Researchers Receive $1.5M NIH Grant to Enhance Guidelines for Ethical Human-Animal Chimera Research
Insoo Hyun, PhD, and colleagues will identify ways of improving existing guidelines and ensuring professional accountability and responsibility in human-animal chimera research. The interdisciplinary bioethics project is supported by a three-year, $1.5 million grant from the National Human Genome…
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New laser breakthrough
Case Western Reserve University researchers, global collaborators, first to demonstrate ‘random, transistor’ laser that can be manipulated at nanoscale In the last half-century, laser technology has grown into a multi-billion-dollar global industry and used in everything from optical-disk drives…
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Senior care meets scientific research
Ohio Living Breckenridge Village, Case Western Reserve University collaborate to open Smart Living Lab to aid residents, academic researchers A diverse group of collaborators posed a novel question over the last year: What if  seniors could test technology designed to improve their lives in…
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Database Funded to Help Researchers Understand the Effect of Bipolar Disorder throughout Adult Lifespan
Martha Sajatovic, MD, has received a three-year, $600,000 grant from the International Society for Bipolar Disorders. She and her colleagues will develop the first-of-its-kind multi-national database that can be used to help researchers address questions about BD throughout the adult lifespan. …