Science + Tech

Bottom Line: Researchers discovered three novel genetic mutations associated with Fuchs endothelial corneal dystrophy, the most common corneal disorder requiring transplantation. Journal in Which the Study was Published: Nature Communications Author: Sudha K. Iyengar, PhD, Professor of…

Recently, I reread the books of Lewis Thomas, MD. These beautiful collections of essays, many originally published in the New England Journal of Medicine as “Notes of a Biology Watcher,” are lyrical reflections on the human condition and the high position of medicine and science therein. Dr.…

A light-sensing pigment found in everything from bacteria to vertebrates can be biochemically manipulated to reset itself, an important therapeutic advantage, according to new research out of Case Western Reserve University School of Medicine. In a study just released from the Proceedings of the…

New study also provides drug screening platform for broad therapeutic development A multi-institutional team led by researchers at Case Western Reserve University School of Medicine have grown stem cells from children with a devastating neurological disease to help explain how different genetic…

Two biophysicists from Case Western Reserve University School of Medicine have used supercomputers to show how cell membranes control the shape, and consequently the function, of a major cancer-causing protein. The protein, a small enzyme called K-Ras, is attached to cell membranes where it senses…

Researchers led by Julian E. Stelzer, PhD, associate professor in the department of physiology and biophysics at Case Western Reserve University School of Medicine, have found a new target for drug developers seeking straightforward ways to improve cardiac output in heart failure patients. In a…

A massive new study involving blood samples from more than 30,000 individuals has identified 13 new genetic risk factors for glioma, the most common type of malignant brain tumor in adults. The study, published in Nature Genetics, reveals specific differences in a person’s DNA that increase…

Case Western Reserve University School of Medicine and the Case Comprehensive Cancer Center have been named to a new colorectal cancer dream team that was announced today at the annual meeting of the American Association for Cancer Research in Washington, D.C. The dream team comprises scientists,…

Case Western Reserve University (CWRU) School of Medicine and the Case Comprehensive Cancer Center (Case CCC) have been named to a prestigious "colorectal cancer dream team" that was announced today at the annual meeting of the American Association for Cancer Research in Washington, D.C. The dream…

Case Western Reserve University and Q2 Pharma Ltd., an Israeli biopharmaceutical company, have signed a two-year option to license small molecule, antivirulence technology to potentially treat bacterial infections such as methicillin-resistant staphylococcus aureus (MRSA), the first known…