Science + Tech

A multicenter team led by Case Western Reserve has demonstrated that brief exposure to a targeted therapy can tell doctors which HER2-negative patients will respond — and which should switch to another kind of treatment.  If confirmed in clinical trials, the discovery would provide physicians…

A Case Western Reserve University graduate student turned a research paper into a field test that quickly determines whether an Asian carp invading Lake Erie is sterile or can reproduce. If proven successful, the technique could save money and time in the effort to keep the carp out of the Great…

Genetics researchers from Case Western Reserve School of Medicine have identified a novel long non-coding RNA (lncRNA), dubbed DACOR1, that has the potential to stymie the growth of tumor cells in the second-most deadly form of cancer in the U.S. — colorectal cancer.  The researchers found that…

Coupling with perovskite solar cell holds potential for cleaner cars and more Liming Dai led the team's research. Consumers aren’t embracing electric cars and trucks, partly due to the dearth of charging stations required to keep them moving. Even the conservation-minded are hesitant to go…

Tadpole size increases but juvenile survival drops Millions of tons of road salt are applied to streets and highways across the United States each winter to melt ice and snow and make travel safer, but the effects of salt on wildlife are poorly understood. A new study by biologists from Case…

Researchers at Case Western Reserve University have developed a magnetic resonance imaging (MRI) contrast agent that detects aggressive breast cancer tumors and micrometastases much smaller than current agents. “Currently, there is no imaging technology in clinical use that can detect tumors or…

The National Institutes of Health (NIH) has awarded $2.3 million to Case Western Reserve to lead a collaborative study of how changes in food options affect residents’ nutritional choices and health over time. Called the Future of Food in Your Neighborhood Study (dubbed foodNEST), the three-year…

Case Western Reserve scientists may have uncovered a molecular mechanism that sets into motion dangerous infection in the feet and hands often occurring with uncontrolled diabetes. It appears that high blood sugar unleashes destructive molecules that interfere with the body’s natural…

Case Western Reserve University scientists have discovered that a protein called Kruppel-like Factor 4 (KLF4) controls mitochondria — the “power plants” in cells that catalyze energy production. Specifically, they determined KLF4’s pivotal role through its absence — that is, the mitochondria…

An algorithm dubbed ENVE could be the Google for genetic aberrations — and it comes from Case Western Reserve. Remember the World Wide Web before the famed search engine? The web offered extraordinary amounts of information, but no consistently reliable way to secure relevant results. Cancer…