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Science + Tech

Peptide Shows Great Promise for Treating Spinal Cord Injury
Case Western Reserve scientists have developed a new chemical compound that shows extraordinary promise in restoring function lost to spinal cord injury. The compound, which the researchers dubbed intracellular sigma peptide (ISP), allowed paralyzed muscles to activate in more than 80 percent of…
Researchers Characterize a Protein Mutation that Alters Tissue Development in Males Before Birth
Case Western Reserve researchers have identified a protein mutation that alters specific gender-related tissue in males before birth and can contribute to the development of cancer as well as other less life-threatening challenges. The discovery marks the latest in a series of findings related to…
Case Western Reserve Malaria Expert Named One of 100 Leading Global Thinkers for 2014
Case Western Reserve malaria specialist Brian T. Grimberg, PhD, is among Foreign Policy magazine’s 100 Leading Global Thinkers of 2014 being honored this evening in Washington, DC. Grimberg of the Center for Global Health and Diseases at Case Western Reserve University School of Medicine will…
Researchers discern the shapes of high-order Brownian motions
For the first time, scientists have vividly mapped the shapes and textures of high-order modes of Brownian motions—in this case, the collective macroscopic movement of molecules in microdisk resonators—researchers at Case Western Reserve University report. To do this, they used a record-setting…
From strangers to mates in 15 minutes
Single gene enables female fruit flies to choose (Mr.) right Ah, to be a fruit fly. No meddling matchmakers, creepy dates or frog kissing. Females process the sights, smell, sounds and touch of love to choose Mr. Right in 15 minutes. Researchers at Case Western Reserve University discovered the…
Laboratory Breakthrough Offers Promise for Spinal Cord Injury Patients to Breathe on Their Own Again
Case Western Reserve researchers have developed a procedure that restores function to muscles involved in the control of breathing – even when they have been paralyzed for more than a year. The breakthrough offers hope that one day patients with severe spinal cord injuries will be able to breathe…
Partnership Pays: Collaboration Among Case Western Reserve, Cuyahoga County, and YMCA of Greater Cleveland Catalyzes More Than $13 Million in Public Health Grants
The Prevention Research Center for Healthy Neighborhoods (PRCHN) at Case Western Reserve University School of Medicine is a key player in nearly $13.32 million in federal grants awarded to improve community health in Northeast Ohio. The Centers for Disease Control and Prevention (CDC) renewed the…
Case Western Reserve University visible at celebration for discovery of cystic fibrosis gene
Faculty and clinicians among those to reflect on CFTR gene discovery 25 years ago and on current treatment advances The discovery of the cystic fibrosis (CF) gene was hailed as a trailblazing breakthrough in 1989. Now, on the 25th anniversary of the discovery of cystic fibrosis transmembrane…
Delivering a One-Two Punch: New Drug Combination Shows Promise as Powerful Treatment for Breast Cancer
The uncontrolled growth of cancer cells arises from their ability to hijack the cell’s normal growth program and checkpoints. Usually after therapy, a second cancer-signaling pathway will open after the primary one shuts down — creating an ingenious escape route for the cancer cell to survive. The…
New Compounds Reduce Debilitating Inflammation
Six Case Western Reserve scientists are part of an international team that has discovered two compounds that show promise in decreasing inflammation associated with diseases such as ulcerative colitis, arthritis and multiple sclerosis. The compounds, dubbed OD36 and OD38, specifically appear to…