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Science + Tech

African-American Study Identifies Four Common Genetic Variants Associated with Blood Pressure
Case Western Reserve University is part of a landmark study that has discovered four novel gene variations  which are associated with blood pressure. The 19-site meta-analysis, involving nearly 30,000 African-Americans, also found that the set of genetic mutations are also associated with blood…
Researchers Discover a New Pathway in Blood Vessel Inflammation and Disease
Case Western Reserve researchers have identified a genetic factor that blocks the blood vessel inflammation that can lead to heart attacks, strokes and other potentially life-threatening events.   The breakthrough involving Kruppel-like factor (KLF) 15 is the latest in a string of discoveries…
Boy Interrupted: Y-chromosome Mutations Reveal Precariousness of Male Development
CLEVELAND – The idea that men and women are fundamentally different from each other is widely accepted. And throughout the world, this has created distinct ideas about which social and physical characteristics are necessary in each gender to maintain healthy human development. However, social…
Insecticide-treated bed nets critical to global elimination of filariasis
The New England Journal of Medicine study finds low-cost tool complements existing mass drug administration strategy An international team of scientists have demonstrated that a simple, low-cost intervention holds the potential to eradicate a debilitating tropical disease that threatens nearly 1.4…
Insecticide-treated Bed Nets Critical to Global Elimination of Filariasis
An international team of scientists have demonstrated that a simple, low-cost intervention holds the potential to eradicate a debilitating tropical disease that threatens nearly 1.4 billion people in more than six dozen countries.   The researchers, including Case Western Reserve University…
Psoriasis Researcher Earns Third NIH Grant in One Year
Dermatology researcher Nicole Ward, PhD, has earned her third National Institutes of Health grant in a year – including two that scored in the first percentile. With this most recent award, an R21, she will investigate the role the nervous system plays in psoriasis – an inflammatory autoimmune…
New Designer Compound Treats Heart Failure by Targeting Cell Nucleus
Researchers from Case Western Reserve University School of Medicine and the Dana-Farber Cancer Institute have made a fundamental discovery relevant to the understanding and treatment of heart failure – a leading cause of death worldwide. The team discovered a new molecular pathway responsible for…
Evolution of Diverse Sex-Determining Mechanisms in Mammals
Scientists historically have argued that evolution proceeds through gradual development of traits. But how can incremental changes apply to the binary switch between two sexes, male or female? Researchers at Case Western Reserve University’s School of Medicine have found that a genetic process…
Harvard expert in glaucoma Douglas Rhee, MD, named Chair of Ophthalmology and Visual Sciences at Case Western Reserve University School of Medicine and University Hospitals Case Medical Center
CLEVELAND -- After an extensive national search, Case Western Reserve University School of Medicine and University Hospitals (UH) CaseMedical Center have named Douglas Rhee, MD, an accomplished glaucoma specialist, eye surgeon and researcher, chair of the Department of Ophthalmology and Visual…
New Approach to Protecting Prion Protein from Altering Shape, Becoming Infectious
CLEVELAND – July 18, 2013 – A team of researchers from Case Western Reserve University School of Medicine have identified a mechanism that can prevent the normal prion protein from changing its molecular shape into the abnormal form responsible for neurodegenerative diseases. This finding,…