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Science + Tech

Synthetic Triterpenoids Show Promise in Preventing Colitis-Associated Colon Cancer
Researchers from Case Western Reserve and Dartmouth universities have shown that a class of small antioxidant molecules carries enormous promise for suppressing colon cancer associated with colitis. These findings, published in an early June edition of the Journal of Clinical Investigation, offer…
Long Non-coding RNAs Can Encode Proteins After All
Case Western Reserve School of Medicine scientists have made an extraordinary double discovery. First, they have identified thousands of novel long non-coding ribonucleic acid (lncRNA) transcripts. Second, they have learned that some of them defy conventional wisdom regarding lncRNA transcripts,…
Family of Proteins Plays Key Role in Cellular Pump Dynamics
Case Western Reserve University scientists have discovered how a family of proteins — cation diffusion facilitators (CDFs) — regulates an important cellular cycle where a cell’s energy generated is converted to necessary cellular functions. The finding has the potential to inform future research…
Cancer Drug Boosts Levels of Vascular-Protective Gene, KLF2
Case Western Reserve University researchers have discovered that an existing drug used to help cancer patients has the potential to protect thousands of others from the often-deadly impact of vascular clots. In 2008, the Food and Drug Administration approved bortezomib (Velcade) to treat multiple…
Stem Cells Hold Keys to Body’s Plan
Case Western Reserve researchers have discovered landmarks within pluripotent stem cells that guide how they develop to serve different purposes within the body. This breakthrough offers promise that scientists eventually will be able to direct stem cells in ways that prevent disease or repair…
Investigators discover how key protein enhances memory and learning
Finding could pave way to cognitive disease therapies Case Western Reserve University researchers discovered that a protein previously implicated in disease plays such a positive role in learning and memory that it may someday contribute to cures of cognitive impairments. The findings regarding…
Physician practice facilitation ensures key medical care reaches children
Discovery could lead to improved preventive medical care delivery processes Recently, a study of more than 16,000 patient visits published online in the journal Pediatrics proved Cuttler’s thesis correct. The lead investigator on the research project, Cuttler succumbed to cancer late last year.…
Student discovers new praying mantis species in Rwanda
Female bush tiger mantis hunts prey on ground and underbrush Circling the light trap used to lure insects out of the thick, wet night in Rwanda’s mountainous Nyungwe Forest National Park, Riley Tedrow reached into the leaf litter on the ground and nabbed a male and female of what turned out to be…
FDA Approves Many Drugs that Predictably Increase Heart and Stroke Risk
The agency charged to protect patients from dangerous drug side effects needs to be far more vigilant when it comes to medications that affect blood pressure. Robert P. Blankfield, MD, MS, a clinical professor of family medicine, issues this call to the U.S. Food and Drug Administration (FDA) in…
Dr. Neal Meropol Honored as American Society of Clinical Oncology Fellow
The American Society of Clinical Oncology (ASCO) will honor Neal J. Meropol, MD, as a Fellow during the May 31 Opening Session of the 2014 ASCO Annual Meeting in Chicago. He will be one of 12 exceptional members to earn the designation of Fellow as a result of their extraordinary volunteer service,…