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Medicine's Andrew Pieper studies drug that reverses Alzheimer's in mice

Media | January 14, 2026 | Story by: Editorial Staff

Experimental drug reverses Alzheimer's in mice

AOL:  Andrew A. Pieper, professor of medicine at the School of Medicine, explained how restoring the brain’s energy balance by maintaining NAD+ balance could prevent and even reverse Alzheimer’s disease. “We found that brains from people and mice with Alzheimer’s show much larger disturbances in NAD+ homeostasis, a vital aspect of brain health, than normal aging causes. That suggested the imbalance might be driving the disease,” said Pieper.

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