Case Comprehensive Cancer Center

Research into stopping tumor growth was recently featured in BBC Science Focus Magazine as one of the world's "20 moments in 2020 to be excited about." A compound that activates an enzyme capable of suppressing tumors was discovered by a cross-institutional team from the University of Michigan and C...

From Cleveland Clinic Lerner Research Institute: Standard-of-care treatment for many cancers includes chemotherapy drug cisplatin which prevents the spread of cancer cells by interrupting DNA replication and damaging the genetic material in rapidly dividing tumor cells. Unfortunately, the drug can c...

Glioblastoma, recognized as the most aggressive primary brain cancer in adults is also known to be among the most immunosuppressive of tumors. A Phase 2 clinical trial of PVSRIPO, a revolutionary viral immunotherapy for cancer treatment, in combination with Keytruda (pembrolizumab) is underway acros...

Case Comprehensive Cancer Center is once again hosting the Cancer Disparities Symposium, March 4-5, 2021. The symposium will take place virtually due to COVID restrictions. However, attendees can expect the same level of high-caliber research and an overall dedication to conquering health disparitie...

Ohio Governor Mike DeWine and Lt. Governor Jon Husted on Monday announced the Cleveland Innovation District, a transformational collaboration of Northeast Ohio's leading healthcare and higher education institutions. The Cleveland Innovation District brings together Case Western Reserve University, ...

Researchers at Cleveland Clinic's Ob/Gyn & Women's Health Institute and Lerner Research Institute recently published a retrospective study in Gynecologic Oncology which found that women with newly diagnosed stage III or IV epithelial ovarian cancer and received antibiotics following cytoreductive su...

I am pleased to announce the appointment of two new leaders to our research programs. Agata Exner, PhD will co-lead the Cancer Imaging Program with Jim Basilion, PhD and Zhenghong Lee, PhD. Dr. Exner is a translational researcher with collaborative industry ties....

Researchers in the Department of Biomedical Engineering at Cleveland Clinic Lerner Research Institute have developed an improved approach to treating actinic keratosis, a pre-cancerous skin condition usually treated with photodynamic therapy that patients often report as painful. Findings from a cl...

Case Western Reserve and partners local and global team up to better predict which patients with oral squamous cell carcinomas will need radiation or chemotherapy after surgery Researchers at Case Western Reserve University and partners in the United States and India are applying the investigative ...

As we end December, I, for one, am glad to see 2020 fade into the rear-view mirror. Almost like the Alfred Hitchcock movie (rear window), the whole year looked and felt wrong—unlike anything we have ever experienced. It threw immense challenges at us, pushed many to our limits, and tested us in ways...