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Clinical and Translational Science Collaborative

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Interview with a KL2 Scholar alum: Exploring early multiple sclerosis treatment strategies
When it comes to initial treatment selection for relapsing-remitting multiple sclerosis (RRMS), there is one question that has yet to be answered: Is it better to start with potentially safer moderately effective disease-modifying treatments (DMTs) or to hit the disease immediately with a high-effic...
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CTSC Regulatory Steering Group convened to promote city-wide interaction and collaboration
Faculty, staff members, and invited guests supporting research administration from all four of our partner institutions convened on Wednesday, August 14, 2019 for the CTSC Regulatory Steering Group Meeting. This gathering of over 20 individuals from Case Western Reserve University, the Cleveland Cli...
KL2 alum helps shed light on vitamin D supplementation and prevention of type 2 diabetes
Sangeeta Kashyap, MD, Department of Endocrinology, Diabetes and Metabolism at the Cleveland Clinic, and CTSC KL2 scholar alum, was part of a large, multi-institution study to determine whether vitamin D supplementation lowers the risk of type 2 diabetes. Their results have been published in the New ...
Risk-period-cohort method has broad implications for examining processes of change over time in longitudinal studies
In epidemiology, gerontology, human development and the social sciences, age-period-cohort (APC) models are used to study the variability in trajectories of change over time. A well-known issue exists in simultaneously identifying age, period and birth cohort effects, namely that the three character...
AI framework can inform radiation therapy dosage using patient medical scans
In a new paper published in Lancet Digital Health, recent CTSC KL2 Scholar grad and radiation oncologist at the Cleveland Clinic, Dr. Mohamed Abazeed and colleagues show that an artificial intelligence (AI) framework can provide personalized radiation dosage based on data from CT scans and electroni...
KL2 Scholar alum uses data to decide when to transfer patients by medical helicopter
The ability to quickly move patients by medical helicopter is especially vital in what is known as the golden hour--that first hour after a traumatic injury, considered the most critical for successful emergency treatment. "For true emergencies, it is quicker and better to transport someone by air,...
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Clinical and Translational Science Collaborative Community and Collaboration component offers funding for translational projects
The Community and Collaboration (C&C) component of the Clinical and Translational Science Collaborative (CTSC) is offering a new funding opportunity intended to support, promote and highlight multi-disciplinary collaborations. The CTSC C&C component will provide pilot funding for a Translational Res...
Modeling healthy eating measures of residents living in food deserts
CTSC Community & Collaboration co-lead and Prevention Research Center for Healthy Neighborhoods Director Elaine Borawski, PRCHN Associate Director Erika Trapl and affiliated faculty member Darcy Freedman are among the co-authors of a paper published in the Journal of the Academy of Nutrition and Die...
The Revised Common Rule: What Happens Now After the Compliance Date?
The revised Common Rule, released by the U.S. Department of Health and Human Services (DHHS), is the first major change to these regulations in more than 25 years. Human research protection professionals are subject to following the revised Common Rule provisions, with a compliance date of January 2...
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Nurses Poised to Take the Lead on Ensuring Patient Safety in U.S. Health Care System
CTSC KL2 Scholar alumna, Mary Dolansky, PhD, RN, FAAN, associate professor at the Frances Payne Bolton School of Nursing at CWRU, co-chaired the May 29-31, 2019 QSEN Rocks International Forum conference at the Hilton Cleveland Downtown. Dr. Dolansky states that “medical error is already the third-l...