Clinical and Translational Science Collaborative

Scientific quality and feasibility are part of ethics review by Institutional Review Boards (IRBs). Scientific Review Committees (SRCs) were proposed to facilitate this assessment by the Clinical and Translational Science Award (CTSA) SRC Consensus Group. This study assessed SRC feasibility and…

The Community & Collaboration Component of the Clinical and Translational Science Collaborative (CTSC) offers four-hour professionally facilitated work sessions for established or emerging interdisciplinary groups of investigators with engaged stakeholders that need time to brainstorm and…

The Community and Collaboration Component (C&C) of the Clinical and Translational Science Collaborative (CTSC) selected two collaborative teams to receive the first round of pilot awards focused on team science with stakeholder engagement. Recipients needed to demonstrate they were an…

The Cleveland Institute for Computational Biology (CICB) is pleased to announce that it has been instrumental in helping to create The Book of OHDSI, 1 st Edition , the first textbook describing the Observational Health Data Sciences and Informatics (OHDSI) community, the OHDSI (OMOP) data…

Charles Bark, MD, CTSC KL2 Scholar alum and an infectious disease specialist in the MetroHealth Medical Center Department of Medicine, was awarded a 5-year $7.2 million NIH grant to study patterns of tuberculosis (TB) transmission in Kampala, Uganda. Decreasing the global burden of TB requires…

When it comes to initial treatment selection for relapsing-remitting multiple sclerosis (RRMS), there is one question that has yet to be answered: Is it better to start with potentially safer moderately effective disease-modifying treatments (DMTs) or to hit the disease immediately with a…

Faculty, staff members, and invited guests supporting research administration from all four of our partner institutions convened on Wednesday, August 14, 2019 for the CTSC Regulatory Steering Group Meeting. This gathering of over 20 individuals from Case Western Reserve University, the Cleveland…

Sangeeta Kashyap, MD, Department of Endocrinology, Diabetes and Metabolism at the Cleveland Clinic, and CTSC KL2 scholar alum, was part of a large, multi-institution study to determine whether vitamin D supplementation lowers the risk of type 2 diabetes. Their results have been published in the New…

In epidemiology, gerontology, human development and the social sciences, age-period-cohort (APC) models are used to study the variability in trajectories of change over time. A well-known issue exists in simultaneously identifying age, period and birth cohort effects, namely that the three…

In a new paper published in Lancet Digital Health, recent CTSC KL2 Scholar grad and radiation oncologist at the Cleveland Clinic, Dr. Mohamed Abazeed and colleagues show that an artificial intelligence (AI) framework can provide personalized radiation dosage based on data from CT scans and…