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Investigators Highlight Potential of Exercise in Addressing Substance Abuse in Teens
Exercise has numerous, well-documented health benefits. Could it also play a role in preventing and reducing substance misuse and abuse in adolescents? This is the intriguing question that a team of investigators from Case Western Reserve University School of Medicine and Cleveland Clinic seeks to a...
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Researchers Inhibit Cancer Metastases via Novel Steps
In one of the first successes of its kind, researchers from Case Western Reserve University School of Medicine and six other institutions have inhibited the spreading of cancer cells from one part of the body to another. In doing so, they relied on a new model of how cancer metastasizes that emphasi...
Case Western Reserve and Sangamo Therapeutics Announce $11 Million NIH Grant for Study of Gene-Edited T Cells for the Viral Eradication of HIV
Case Western Reserve University and Sangamo Therapeutics, Inc. (Nasdaq: SGMO) today announced the award of an $11 million grant from the National Institutes of Health for a planned study of gene-edited T cells designed to eradicate persistent HIV infection in patients receiving anti-retroviral thera...
Full-length Serotonin Receptor Structure Seen for First Time
A team of researchers from Case Western Reserve University School of Medicine have used Nobel prize-winning microscope technology to see full length serotonin receptors for the first time. The tiny proteins—approximately a billionth of a meter long—are common drug targets, despite limited available ...
Marlene R. Miller, MD, MSc, Appointed Pediatrician-in-Chief, Chair of Pediatrics at University Hospitals Rainbow Babies & Children’s Hospital
Marlene R. Miller, MD, MSc, has been appointed Pediatrician-in-Chief for University Hospitals and chair of the Department of Pediatrics at University Hospitals Rainbow Babies & Children’s Hospital (UH Rainbow). Dr. Miller will also be nominated for appointment by President Barbara R. Snyder as chair...
Researchers Reverse Symptoms in Neurologic Disease Model
It is a parent’s nightmare: a child is born apparently healthy, then stops meeting developmental milestones at one year old. Her verbal and motor skills vanish, and irregular breathing, seizures, and a host of other problems appear. The cause is Rett syndrome—a devastating genetic, neurologic disord...
Researchers Receive $6.5 Million NIH Grant to Use Big Data to Tackle Psoriasis
An experienced interdisciplinary team of psoriasis and computational researchers from Case Western Reserve University School of Medicine (CWRU SOM) and University Hospitals Cleveland Medical Center (UHCMC) has received a $6.5M, 5-year grant from the National Institute of Arthritis, Musculoskeletal a...
Alex Huang, MD, PhD, Receives $450,000 from Pediatric Cancer Research Foundation
Alex Huang, MD, PhD Leading cancer researcher, Alex Huang MD, PhD, has received a $450,000 Basic Science grant from Pediatric Cancer Research Foundation to study targeted approaches for effectively eliminating metastatic osteosarcoma. “We’re very excited to study an important cancer that...
Researchers Borrow from AIDS Playbook to Tackle Rheumatic Heart Disease: Taking Services to the People
Emmy Okello, MBChB, PhD performs echocardiographic screening for rheumatic heart disease. Billions of US taxpayer dollars have been invested in Africa over the past 15 years to improve care for millions suffering from the HIV/AIDS epidemic; yet health systems on the continent continue to ...
Researchers Discover New Enzymes Central to Cell Function
Doctors have long treated heart attacks, improved asthma symptoms, and cured impotence by increasing levels of a single molecule in the body: nitric oxide. The tiny molecule can change how proteins function. But new research featured in Molecular Cellsuggests supplementing nitric oxide—NO—is only t...