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Case Western Reserve Scientist Captures Prestigious NIH Director’s New Innovator Award
For the second consecutive year, a Case Western Reserve University School of Medicine researcher has landed one of the year’s much-coveted Director’s New Innovator Awards from the National Institutes of Health (NIH). Principal investigator Rong Xu, PhD, assistant professor of medical informatics, wi...
Case Western Reserve University on Track to Become No. 1 Synchrotron Lab in World
Case Western Reserve University’s synchrotron facility at Brookhaven National Laboratory is on its way to becoming the No. 1 beamline facility for biology in the world by early 2016, thanks to a jumpstart grant of $4.6 million from the National Institute of Biomedical Imaging and Bioengineering (NIB...
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Curcumin, Special Peptides Boost Cancer-Blocking PIAS3 to Neutralize Cancer-Activating STAT3 in Mesothelioma
A common Asian spice and cancer-hampering molecules show promise in slowing the progression of mesothelioma, a cancer of the lung’s lining often linked to asbestos. Scientists from Case Western Reserve University and the Georg-Speyer-Haus in Frankfurt, Germany, demonstrate that application of curcum...
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Leaky Gut — A Source of Non-AIDS Complications in HIV-Positive Patients
Human immunodeficiency virus (HIV) infection is no longer a fatal condition, thanks to newer medications inhibiting the retrovirus, but a puzzling phenomenon has surfaced among these patients — non-AIDS complications. Scientists at Case Western Reserve University School of Medicine have resolved the...
Protective Hinge Process Enables Insulin to Bind to Cells
Since its landmark discovery in 1922, insulin has improved the health and extended the lives of more than 500 million people worldwide with diabetes mellitus. Yet the question of how this key hormone binds to its target cells in the body’s organs has posed an enduring scientific mystery. A global te...
Neighborhood Connections brings a 12-foot teepee to Wade Oval Wednesday July 30
Neighborhood Connections, the small-grants and grassroots community-building program affiliated with the Cleveland Foundation, is bringing a 12-foot teepee to the WOW! Wade Oval Wednesday concert on July 30. People will have an opportunity to share their thoughts about what makes for a healthy Great...
Cuyahoga County High School Students Smoking at the Same Rate as Adults
Cuyahoga County high school students are smoking tobacco products at the same rate as adults in the county, according to new data from the Prevention Research Center for Healthy Neighborhoods (PRCHN) at Case Western Reserve University. In 2013, more than 22 percent, or one in five high school studen...
International Research Team Discovers Genetic Dysfunction Connected to Hydrocephalus
The mysterious condition once known as “water on the brain” became just a bit less murky this week thanks to a global research group led in part by a Case Western Reserve researcher. Professor Anthony Wynshaw-Boris, MD, PhD, is the co-principal investigator on a study that illustrates how the domino...
Bacteria Hijack Plentiful Iron Supply Source to Flourish
In an era of increasing concern about the prevalence of antibiotic-resistant illness, Case Western Reserve researchers have identified a promising new pathway to disabling disease: blocking bacteria’s access to iron in the body. The scientists showed how bacterial siderophore, a small molecule, cap...
Case Western Reserve University Researchers and Collaborators Receive $12.6 Million NIH Grant to Study Genetics of Alzheimer’s Disease
Researchers from Case Western Reserve University School of Medicine are part of a five-university collaboration receiving a $12.6 million, four-year grant from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), to identify rare genetic variants that may either pr...