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Cleveland Clinic, Case Western Reserve School of Medicine Team Discovers Key Mechanisms to Inhibit Triple Negative Breast Cancers
A team of researchers from the Cleveland Clinic and Case Western Reserve School of Medicine have identified critical complex mechanisms involved in the metastasis of deadly “triple negative” breast cancers (TNBC). These tumors are extremely difficult to treat, frequently return after remission, and...
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Breakthrough in Understanding the Secret Life of Prion Molecules
New research from David Westaway, PhD, of the University of Alberta and Jiri Safar, MD, Case Western Reserve University School of Medicine has uncovered a quality control mechanism in brain cells that may help keep deadly neurological diseases in check for months or years. The findings, published i...
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Alex's Lemonade Stand Foundation Grants $625,000 to Case Western Reserve School of Medicine
Philadelphia, PA (January 14, 2014) – In an effort to bring the latest treatments to more children with cancer now, Alex’s Lemonade Stand Foundation (ALSF) has announced the awarding of six new Phase I/II Infrastructure Grants to researchers at leading hospitals and institutions across the country. ...
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Nature Study Discovers Chromosome Therapy to Correct a Severe Chromosome Defect
Geneticists from Ohio, California and Japan joined forces in a quest to correct a faulty chromosome through cellular reprogramming. Their study, published online today in Nature, used stem cells to correct a defective “ring chromosome” with a normal chromosome. Such therapy has the promise to correc...
Researchers at Case Comprehensive Cancer Center Discover Ovarian Cancer Biomarker
Researchers at Case Western Reserve University have identified a microRNA biomarker that shows promise in predicting treatment response in the most common form of ovarian cancer – a breakthrough that has the potential to improve outcomes for patients with the disease. A CWRU research team led by An...
Case Western Reserve Researchers Uncover Critical Interaction in Heart Drugs
Researchers at Case Western Reserve University School of Medicine and Temple University School of Medicine have gained new insight into how classic heart drugs work—and it’s not the way they thought. Their discovery – on the role nitric oxide (NO) plays in blocking the effect of an enzyme called GR...
Common Disorders: It’s Not the Genes Themselves, But How They Are Controlled
Many rare disorders are caused by gene mutation, like sickle cell anemia. Yet until now the underlying genetic cause of more common conditions – for example, rheumatoid arthritis – has evaded scientists for years. New research from Case Western Reserve University School of Medicine to appear in the...
Beta-Carotene Beneficial for Tackling Vitamin A Deficiency
A Case Western Reserve University School of Medicine study in the November 22 issue of Journal of Biological Chemistry, explains how vitamin A is generated from beta carotene, its dietary precursors. The discovery sheds new light into how beta carotene’s enzymes are utilized differently contributing...
Clevelanders: Lighting Up in a New Way
A new data brief released by the Prevention Research Center for Healthy Neighborhoods at Case Western Reserve University (PRCHN) shows that more than one-in-five African-American young adults in Cleveland, ages 18 to 29, routinely uses little cigars. Additional findings detailed in the PRCHN dat...
Case Western Reserve, Cleveland Clinic and University Hospitals Launch Innovative Venture to Advance Analysis of Medical Data
Case Western Reserve, Cleveland Clinic and University Hospitals today announced the launch of the Institute of Computational Biology, an innovative venture designed to enhance the institutions’ ability to draw actionable insights from the oceans of medical information each already possesses. Renown...