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Non-specific and Specific RNA Binding Proteins Found to be Fundamentally Similar
Researchers from Case Western Reserve University School of Medicine have found unexpected similarities between proteins that were thought to be fundamentally different. The team studied how proteins bind to RNA, a process required for gene expression. It is known that some proteins only bind RNA...
Case Western Reserve Named Part of $10.2 Million Innovation Alliance
CLEVELAND – October 1, 2013 – Case Western Reserve University is among the major partners in a $10.2 million Ohio project designed to speed medical breakthroughs to patients – one of only three to win federal funding this year. The Cleveland Clinic is leading the initiative, which includes Case Wes...
Breakthrough Offers First Direct Measurement of Spinal Cord Myelin in Multiple Sclerosis
Researchers have made an exciting breakthrough – developing a first-of-its-kind imaging tool to examine myelin damage in multiple sclerosis (MS). An extremely difficult disease to diagnose, the tool will help physicians diagnose patients earlier, monitor the disease’s progression, and evaluate thera...
African-American Study Identifies Four Common Genetic Variants Associated with Blood Pressure
Case Western Reserve University is part of a landmark study that has discovered four novel gene variations which are associated with blood pressure. The 19-site meta-analysis, involving nearly 30,000 African-Americans, also found that the set of genetic mutations are also associated with blood pres...
Boy Interrupted: Y-chromosome Mutations Reveal Precariousness of Male Development
CLEVELAND – The idea that men and women are fundamentally different from each other is widely accepted. And throughout the world, this has created distinct ideas about which social and physical characteristics are necessary in each gender to maintain healthy human development. However, social revol...
Insecticide-treated Bed Nets Critical to Global Elimination of Filariasis
An international team of scientists have demonstrated that a simple, low-cost intervention holds the potential to eradicate a debilitating tropical disease that threatens nearly 1.4 billion people in more than six dozen countries. The researchers, including Case Western Reserve University School...
Psoriasis Researcher Earns Third NIH Grant in One Year
Dermatology researcher Nicole Ward, PhD, has earned her third National Institutes of Health grant in a year – including two that scored in the first percentile. With this most recent award, an R21, she will investigate the role the nervous system plays in psoriasis – an inflammatory autoimmune disea...
New Designer Compound Treats Heart Failure by Targeting Cell Nucleus
Researchers from Case Western Reserve University School of Medicine and the Dana-Farber Cancer Institute have made a fundamental discovery relevant to the understanding and treatment of heart failure – a leading cause of death worldwide. The team discovered a new molecular pathway responsible for ca...
Evolution of Diverse Sex-Determining Mechanisms in Mammals
Scientists historically have argued that evolution proceeds through gradual development of traits. But how can incremental changes apply to the binary switch between two sexes, male or female? Researchers at Case Western Reserve University’s School of Medicine have found that a genetic process among...
Harvard expert in glaucoma Douglas Rhee, MD, named Chair of Ophthalmology and Visual Sciences at Case Western Reserve University School of Medicine and University Hospitals Case Medical Center
CLEVELAND -- After an extensive national search, Case Western Reserve University School of Medicine and University Hospitals (UH) CaseMedical Center have named Douglas Rhee, MD, an accomplished glaucoma specialist, eye surgeon and researcher, chair of the Department of Ophthalmology and Visual Scien...