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Serotonin-induced activation of serotonin (3A) receptors Serotonin (3A) receptors are common drug targets in the treatment of pain, gastrointestinal dysfunctions, and mood disorders yet little is known about their three-dimensional structure. Details about serotonin receptor structures…

While growing up in Alaska, Timothy Beal was steeped in a conservative evangelical community with a fondness and fear of Revelation, the last book of the Bible offering a potent brew of hellfire and redemption through a thick tangle of verses violent, bewildering and poetic. By adulthood,…

Frances Payne Bolton School of Nursing works with The John A. Hartford Foundation, Institute for Healthcare Improvement to enhance Age-Friendly care at MinuteClinic locations The Frances Payne Bolton School of Nursing at Case Western Reserve University is working with MinuteClinic, the retail…

Tissue from a mouse that has a functional Dazl gene, with fluorescent-labeled germ cells (left), and tissue from a mouse lacking the Dazl gene (right). A single protein regulates a battery of key genes inside developing sperm, according to a new study out of Case Western Reserve…

Case Western Reserve scientists study acrobatic maneuvers of common flesh flies, offer first proofs of 70-year-old theory on nervous system controlling body rotations A common flesh fly takes off and maneuvers effortlessly, her head and body steadied by a hidden, minuscule gyroscope-like structure…

Insoo Hyun, PhD, and colleagues will identify ways of improving existing guidelines and ensuring professional accountability and responsibility in human-animal chimera research. The interdisciplinary bioethics project is supported by a three-year, $1.5 million grant from the National Human Genome…

Morgenthaler-Pavey Startup Competition offers $50,000 in prize money—and new perks for finalists The six finalists of the upcoming Morgenthaler-Pavey Startup Competition will not only compete for $50,000 in winnings, they will also receive free legal and entrepreneurial services and experience by…

Case Western Reserve University researchers, global collaborators, first to demonstrate ‘random, transistor’ laser that can be manipulated at nanoscale In the last half-century, laser technology has grown into a multi-billion-dollar global industry and used in everything from optical-disk drives…

Ohio Living Breckenridge Village, Case Western Reserve University collaborate to open Smart Living Lab to aid residents, academic researchers A diverse group of collaborators posed a novel question over the last year: What if  seniors could test technology designed to improve their lives in…

Martha Sajatovic, MD, has received a three-year, $600,000 grant from the International Society for Bipolar Disorders. She and her colleagues will develop the first-of-its-kind multi-national database that can be used to help researchers address questions about BD throughout the adult lifespan. …