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Case Western Reserve Researcher Outlines Road Map for Addressing Ethical Concerns Tied to Research on Combination Human-Animal Embryos
Insoo Hyun, PhD, associate professor of bioethics at the School of Medicine of Case Western Reserve University, has proposed a framework for addressing ethical questions surrounding potentially revolutionary research on part-human, part-animal embryos, which can be produced when human stem cells…
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Art rendered in paint, teeth and fur—and rooted in a Cleveland life
Henry Adams catalogues the first-ever retrospective of artist Dexter Davis Dexter Davis spends his days as a guard at the Cleveland Museum of Art, roaming its galleries and protecting prized works, including one of his own. As a Cleveland-based artist of national significance, Davis is the…
Case Western Reserve Researchers Receive Major NIH Renewal Grant to Build on Progress in Understanding Crohn's Disease
Fabio Cominelli, MD, PhD, a professor in the departments of Medicine and Pathology at Case Western Reserve University School of Medicine and Director of Case’s Digestive Health Research Institute, has received a five-year renewal program project grant totaling $9.7 million from the National…
Case Western Reserve University Scientists Uncover Common Cell Signaling Pathway Awry in Some Types of Autism
Brain cells grow faster in children with some forms of autism due to distinct changes in core cell signaling patterns, according to research from the laboratory of Anthony Wynshaw-Boris, MD, PhD, chair of the department of genetics and genome sciences at Case Western Reserve University School of…
Case Western Reserve University Researchers Identify New Drug Cocktail to Protect Mouse Retinas, Potentially Avoiding Blindness
In microseconds, every light ray that enters the eye triggers an explosion of coordinated cellular events. Entering light rays focus on a light-sensitive tissue at the back of the eye called the retina while nearby nerve cells convert the rays into cascades of signals that travel through the optic…
Fused Genes Found in Esophageal Cancer Cells Offer New Clues on Disease Mechanisms
Despite years of research, cellular mechanisms contributing to cancers like esophageal adenocarcinoma have remained elusive. What has puzzled researchers was how genes in the healthy cells lining the esophagus turned the normal cells into malignant ones. Now, researchers from Case Western Reserve…
Case Western Reserve University Researchers Identify Protein that Delays Type 1 Diabetes Onset in New Mouse Model
A new study reveals a counterintuitive cellular strategy that may protect insulin-producing cells from destruction during type 1 diabetes. Type 1 diabetes is an autoimmune disease that accounts for about 5% of the nearly 30 million diagnosed cases of diabetes in the United States, according to the…
Fluoride Consumption Linked to Diabetes Using Mathematical Models
Water fluoridation prevents dental cavities, which are a costly public health concern. But despite the benefits supplemental water fluoridation remains a controversial subject. Some indicate it may cause long term health problems, but studies reporting side effects have been minimal or…
Researchers Restore Drug Sensitivity in Breast Cancer Tumors
A team of Case Western Reserve University School of Medicine cancer researchers has uncovered one way certain tumors resist vital medication. In the study published in Oncotarget, the researchers studied tumor biopsies collected from breast cancer patients before and after treatment with the go-to…
Scientists Keep a Molecule from Moving Inside Nerve Cells to Prevent Cell Death
Amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease) is a progressive disorder that devastates motor nerve cells. People diagnosed with ALS slowly lose the ability to control muscle movement, and are ultimately unable to speak, eat, move, or breathe. The cellular mechanisms behind ALS are…