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Accounting for Racial Inequity in Clinical Trials: Dr. Jackson T. Wright Jr. Honored for Reducing Cardiovascular Disease among African Americans
When Jackson T. Wright Jr. MD, PhD, began practicing medicine in the 1980’s, physicians knew that the risks of high blood pressure were greater in African Americans compared to Caucasians. But what was not known was the dramatic difference in effective prevention and treatment strategies between…
Protein Movement of Hair Bundles in the Inner Ear May Preserve Hearing for Life
Hearing is made possible when hair bundles protruding from the tops of hair cells capture the energy of sound waves, converting them into electrical signals that stimulate the auditory nerve to the brain. These hair bundles are made up of individual hair-like projections, or stereocilia, which sway…
Study aims to document return on investment to U.S. employers who train registered apprentices
CWRU Weatherhead School of Management Economics Professor Susan Helper has key role in collaborative national research Weatherhead School of Management Economics Professor Susan Helper will play a lead role on a team that began developing the research the past two years, while Helper was on…
Case Western Reserve receives $2 million for smoking cessation research
A Case Western Reserve University School of Medicine team received $2 million from the Patient-Centered Outcomes Research Institute (PCORI) to study a combination approach to help patients stop smoking, particularly those who are socially and economically disadvantaged. The project involves…
Biomarker may predict which HER2-negative breast cancer patients will benefit from targeted therapy
A multicenter team led by Case Western Reserve has demonstrated that brief exposure to a targeted therapy can tell doctors which HER2-negative patients will respond — and which should switch to another kind of treatment.  If confirmed in clinical trials, the discovery would provide physicians…
Case Western Reserve scientists discover long-sought genetic mechanism for cancer progression
Genetics researchers from Case Western Reserve School of Medicine have identified a novel long non-coding RNA (lncRNA), dubbed DACOR1, that has the potential to stymie the growth of tumor cells in the second-most deadly form of cancer in the U.S. — colorectal cancer.  The researchers found that…
Legal research paper: U.S. has common law trust obligation to African-Americans 150 years after slavery ended
Case Western Reserve University School of Law faculty member Ayesha Bell Hardaway began reparations research as CWRU law student This year marks the 150-year anniversary of the abolition of slavery in America. Over the years, there have been numerous unsuccessful attempts to secure reparations for…
Case Western Reserve receives $2.3 million federal grant to fund nutritious food access study in Cleveland and Columbus
The National Institutes of Health (NIH) has awarded $2.3 million to Case Western Reserve to lead a collaborative study of how changes in food options affect residents’ nutritional choices and health over time. Called the Future of Food in Your Neighborhood Study (dubbed foodNEST), the three-year…
High blood sugar of diabetes can cause immune system malfunction, leading to more infection and slower wound healing
Case Western Reserve scientists may have uncovered a molecular mechanism that sets into motion dangerous infection in the feet and hands often occurring with uncontrolled diabetes. It appears that high blood sugar unleashes destructive molecules that interfere with the body’s natural…
Key protein drives ‘power plants’ that fuel cells in heart and other key systems in the body
Case Western Reserve University scientists have discovered that a protein called Kruppel-like Factor 4 (KLF4) controls mitochondria — the “power plants” in cells that catalyze energy production. Specifically, they determined KLF4’s pivotal role through its absence — that is, the mitochondria…