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Genetic Regulator of Fat Metabolism and Muscle Fitness Discovered
CLEVELAND - While exercise is accepted universally as the most beneficial prescription physicians can write for patients, little is known about the molecular mechanisms that generate its widespread health benefits. Researchers from Case Western Reserve School of Medicine have shed light on this…
Researchers Develop First “Theranostic” Treatment for Acute Lymphoblastic Leukemia (ALL)
CLEVELAND - A team of researchers at Case Western Reserve University School of Medicine has developed the first “theranostic” agent for the treatment of acute lymphoblastic leukemia (ALL). ALL is the most common type of childhood cancer diagnosed in approximately 5,000 new cases each year in the…
From Mouse to Man: Circadian Nitrogen Balance Impacts Survival and Susceptibility to Common Diseases
CLEVELAND - Researchers at Case Western Reserve University School of Medicine demonstrated that nitrogen balance, the process of utilizing amino acids and disposing of their toxic byproducts, occurs with a precise 24-hour rhythm – also known as circadian rhythm – in mammals. Disruption of this…
First Breakdown of Public Health Data for Cleveland Neighborhoods
CLEVELAND - Today, the Prevention Research Center for Healthy Neighborhoods of Case Western Reserve University release new health data from Cleveland neighborhood groups on three of the most pressing public health concerns: obesity, hypertension, and diabetes. The three data briefs – statistical…
First and Only Study on Harmful Effects of Infants Prenatally Exposed to Ecstasy
CLEVELAND - A study led by Case Western Reserve University School of Medicine, in collaboration with the University of East London UK, and Swansea University UK, is the first to show the effects of the drug ecstasy on fetal and infant development. Ecstasy is a stimulant and hallucinogen, and is…
Circadian Rhythms Linked to Sudden Cardiac Death, Study Finds
CLEVELAND - A fundamental discovery reported in the March 1st issue of the journal Nature, uncovers the first molecular evidence linking the body’s natural circadian rhythms to sudden cardiac death (SCD). Ventricular arrhythmias, or abnormal heart rhythms, are the most common cause of sudden…
Drug Quickly Reverses Alzheimer’s Symptoms in Mice
CLEVELAND - Neuroscientists at Case Western Reserve University School of Medicine have made a dramatic breakthrough in their efforts to find a cure for Alzheimer’s disease. The researchers’ findings, published in the journal Science, show that use of a drug in mice appears to quickly reverse the…
Emergency Departments’ Quality Evaluation Requires Hospital-wide Effort
CLEVELAND - Time can be important in an emergency department especially in a busy Level 1 Trauma Center like MetroHealth Medical Center in Cleveland, when getting patients appropriate care is essential. However, when the quality of an emergency department is judged by a patient’s length of stay,…
$6.75M Awarded to Case Western Reserve to Study IBD
CLEVELAND - Investigators at Case Western Reserve University School of Medicine received a $6.75 million Program Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to study the role of innate immunity in inflammatory bowel disease (IBD). For years,…
Congress’s role in world financial matters explored in new book
In 2008, the U.S. recession put Europe’s economy in flux. Now, what’s happening in European countries like Greece, Spain, Portugal and Ireland raises anxiety levels about a potential blow to the rocky U.S. economy. The International Monetary Fund may be able to throw a lifeline to the struggling…