Researchers from Case Western Reserve University and the University of Cincinnati received a grant from the Air Force Research Laboratory to develop and test platelet-inspired nanotherapeutics for treating traumatic brain injuries (TBI) and hemorrhages, particularly in complex injury scenarios.
Led by CWRU's Anirban Sen Gupta, professor in the Department of Biomedical Engineering, the team created synthetic platelets designed to mimic the diverse functions of natural platelets, like stabilizing clots and reducing bleeding. This innovation addresses limitations of traditional blood transfusions, offering potential benefits in emergency settings and during mass casualty events, with the broader goal of improving trauma care.