Take a look at some of the grants and manuscripts that demonstrate the impact of our work in the Research Institute for Children’s Health at Case Western Reserve University School of Medicine.
Presentations
Rebecca Darrah presented one of the Plenary talks at the 2022 North American Cystic Fibrosis Conference.
One of our 2022 Summer Students presented a poster at the 2022 North American Cystic Fibrosis Conference. Loss of angiotensin II type-2 receptor confers protection from hepatic steatosis and mortality in ketogenic cystic fibrosis mice
Manuscripts
Plona, K., Eastman, J. and Drumm, ML. Classifying molecular phenotypes of G6PC variants for pathogenic properties and to guide therapeutic development. Journal of Inherited Metabolic Diseases Reports, 2021.
Grants
April 2022
- Altered Circadian Rhythm Regulation in Cystic Fibrosis, National Institutes of Health, $2,504,828
- CWRU Therapeutics Pipeline for Genetic Disease, JobsOhio, $230,000.
May 2022
- Editing disease-causing CFTR alleles caused by segmental duplications, Cystic Fibrosis Foundation, $336,000
July 2022
- Hartwell postdoctoral fellowship for Glycogen Storage Disease 1A, The Hartwell Foundation, $100,000.
January 2023
- Addressing barriers to delivery and editing for Cystic Fibrosis, Cystic Fibrosis Foundation, $3,158,363.