Primary Training Faculty Translational Pathobiology Research
Leslie Bruggeman, PhD
Cleveland Clinic
Email: bruggel@ccf.org
Phone: 216.442.8516
Kidney
Interests: host pathology, host genetics, virology in HIVAN; APOL1 in glomerular disease; chronic kidney diseases; renal cell biology
Sanjay Gupta, PhD
Case Western Reserve University
Urology
Interests: TRPC channels; role of TRPC in hyper-inflammatory states; oxidative stress and Ca2+ signaling mechanisms in ion dyshomeostasis
Ketih McCrae
Cleveland Clinic
Phone: 216.444.6833
Hematology
Interests: Hemophilia; hypercoag; thrombotic microangiopathies; extracellular vesicles in thrombosis; immune cell crosstalk with platelets; arterial thrombosis
Marvin Nieman
Case Western Reserve University
Email: nieman@case.edu
Phone: 216.368.0250
Hematology
Interests: Thrombin signaling through protease activated receptor 4 and mechanisms by which platelets adhere to and communicate
Andrew Resnick, PhD
Cleveland State University
Email: a.resnick@csuohio.edu
Phone: 216.687.2437
Kidney
Interests: ciliary function; optical trapping
Alvin Schmaier
University Hospitals
Phone: 216.539.5065
Hematology
Interests: Renin angiotensin systems, extracellular vesicles in thrombosis, management of congenital & acquired hemophilia and management of hypercoagulation
William Shilling, PhD
Case Western Reserve University
Kidney
Interests: TRPC channels; role of TRPC in hyper-inflammatory states; oxidative stress and Ca2+ signaling mechanisms in ion dyshomeostasis
Bing-Cheng Wang, PhD
Case Western Reserve University
Email: bxw14@case.edu
Phone: 216.778.4365
Kidney
Interests: epithelial cell adhesion and migration
Secondary Training Faculty Participating in Collaborative Projects with investigators studying Translational Pathobiology
- Umut Gurkan, Ph.D. Benign Hematology red blood cell structure-function and survival; crosstalk of innate immune cells with platelets and the coagulation system
- Walter Boron, M.D., Ph.D. Kidney regulation of renal ion transport by angiotensin II; proteins sensing respiratory acidosis and alkalosis; physiological roles of gas channels
- Anton Komar, Ph.D. Benign Hematology of protein synthesis; protein folding; translational control of gene expression
- George Dubyak, Ph.D. Benign Hematology role of gasdermin in cell death
- Evi Stavrou, M.D. Benign Hematology Factor XII functions in diabetic skin wound healing; crosstalk of innate immune cells with platelets and the coagulation system
- Jun Qin, PhD. Benign Hematology atomic-level visualization of protein-protein interactions in thrombosis and cardiac failure
- Thomas Gerken, Ph.D. Benign Hematology O-linked glycan impact on protein structure