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Health + Wellness

CWRU researchers find high blood sugar of diabetes can cause immune system malfunction
Case Western Reserve scientists show how sugar-derived molecules can weaken infection-fighting antimicrobial beta-defensin peptides Case Western Reserve University scientists may have uncovered a molecular mechanism that sets into motion the dangerous infection in the feet and hands that often occur...
Building confidence can help people with MS live fuller, healthier lives, CWRU researchers report
The physical symptoms of weakness and fatigue from multiple sclerosis (MS) can rock a person’s confidence and ability to engage in what he or she feels is important, from being a good parent and friend to taking up a hobby, according to Matthew Plow, assistant professor from Case Western Reserve Uni...
Researchers find key protein drives "power plants" that fuel cells in heart and other key systems in the body
Case Western Reserve discovery explains KLF4 and mitochondrial connection in heart failure Case Western Reserve University scientists have discovered that a protein called Kruppel-like Factor 4 (KLF4) controls mitochondria—the “power plants” in cells that catalyze energy production. Specifically, th...
CWRU dental researcher contributes to sisters’ case study of rare genetic syndrome
Physicians and dentists sharing information about rarely seen diseases can help future health-care specialists when patients seek help with unusual symptoms. Dental professionals recently received information from periodontists from Case Western Reserve University School of Dental Medicine and the ...
Case Western Reserve receives $2.3 million federal grant to fund nutritious food access study in Cleveland and Columbus
The National Institutes of Health (NIH) has awarded $2.3 million to Case Western Reserve to lead a collaborative study of how changes in food options affect residents’ nutritional choices and health over time. Called the Future of Food in Your Neighborhood Study (dubbed foodNEST), the three-year stu...
High blood sugar of diabetes can cause immune system malfunction, leading to more infection and slower wound healing
Case Western Reserve scientists may have uncovered a molecular mechanism that sets into motion dangerous infection in the feet and hands often occurring with uncontrolled diabetes. It appears that high blood sugar unleashes destructive molecules that interfere with the body’s natural infection-contr...
Key protein drives ‘power plants’ that fuel cells in heart and other key systems in the body
Case Western Reserve University scientists have discovered that a protein called Kruppel-like Factor 4 (KLF4) controls mitochondria — the “power plants” in cells that catalyze energy production. Specifically, they determined KLF4’s pivotal role through its absence — that is, the mitochondria malfunc...
An alert for parents: CWRU nursing school researcher raises awareness of flame-retardant dangers in household products
Parents might be surprised to learn their cellphones, living room sofas, baby carriers, bouncy baby chairs and even some pizza boxes may contain chemicals harmful to young children, according to Case Western Reserve University nursing school researcher Laura Distelhorst. Distelhorst, an instructor ...
Novel algorithm identifies DNA copy-number landscapes in African-American colon cancers
An algorithm dubbed ENVE could be the Google for genetic aberrations—and it comes from Case Western Reserve University. Remember the World Wide Web before the famed search engine? The web offered extraordinary amounts of information, but no consistently reliable way to secure relevant results. Can...
Novel algorithm identifies DNA copy-number landscapes in African American colon cancers
An algorithm dubbed ENVE could be the Google for genetic aberrations — and it comes from Case Western Reserve. Remember the World Wide Web before the famed search engine? The web offered extraordinary amounts of information, but no consistently reliable way to secure relevant results. Cancer resea...