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Health + Wellness

Unconscious Bias: Cancer Clinical Trial Disparities in Racial and Ethnic Minority Populations
Prepared by Aaron McCorkle, BA – Cleveland Clinic Foundation Unconscious Bias and Health Disparities Implicit social cognition, or unconscious bias, allows individuals to use portions of prior experiences to affect performance, although it may not be introspectively realized (Greenwald &…
CWRU scientists discover genetic mechanism for cancer progression
Action of a key lncRNA different in colon cancer versus normal colon tissue Genetics researchers from Case Western Reserve University School of Medicine have identified a novel long non-coding RNA (lncRNA), dubbed DACOR1, that has the potential to stymie the growth of tumor cells in the…
Case Western Reserve scientists discover long-sought genetic mechanism for cancer progression
Genetics researchers from Case Western Reserve School of Medicine have identified a novel long non-coding RNA (lncRNA), dubbed DACOR1, that has the potential to stymie the growth of tumor cells in the second-most deadly form of cancer in the U.S. — colorectal cancer.  The researchers found that…
CWRU researchers find high blood sugar of diabetes can cause immune system malfunction
Case Western Reserve scientists show how sugar-derived molecules can weaken infection-fighting antimicrobial beta-defensin peptides Case Western Reserve University scientists may have uncovered a molecular mechanism that sets into motion the dangerous infection in the feet and hands that often…
Building confidence can help people with MS live fuller, healthier lives, CWRU researchers report
The physical symptoms of weakness and fatigue from multiple sclerosis (MS) can rock a person’s confidence and ability to engage in what he or she feels is important, from being a good parent and friend to taking up a hobby, according to Matthew Plow, assistant professor from Case Western Reserve…
Researchers find key protein drives "power plants" that fuel cells in heart and other key systems in the body
Case Western Reserve discovery explains KLF4 and mitochondrial connection in heart failure Case Western Reserve University scientists have discovered that a protein called Kruppel-like Factor 4 (KLF4) controls mitochondria—the “power plants” in cells that catalyze energy production. Specifically,…
CWRU dental researcher contributes to sisters’ case study of rare genetic syndrome
Physicians and dentists sharing information about rarely seen diseases can help future health-care specialists when patients seek help with unusual symptoms. Dental professionals recently received information from periodontists from Case Western Reserve University School of Dental Medicine and the…
Case Western Reserve receives $2.3 million federal grant to fund nutritious food access study in Cleveland and Columbus
The National Institutes of Health (NIH) has awarded $2.3 million to Case Western Reserve to lead a collaborative study of how changes in food options affect residents’ nutritional choices and health over time. Called the Future of Food in Your Neighborhood Study (dubbed foodNEST), the three-year…
High blood sugar of diabetes can cause immune system malfunction, leading to more infection and slower wound healing
Case Western Reserve scientists may have uncovered a molecular mechanism that sets into motion dangerous infection in the feet and hands often occurring with uncontrolled diabetes. It appears that high blood sugar unleashes destructive molecules that interfere with the body’s natural…
Key protein drives ‘power plants’ that fuel cells in heart and other key systems in the body
Case Western Reserve University scientists have discovered that a protein called Kruppel-like Factor 4 (KLF4) controls mitochondria — the “power plants” in cells that catalyze energy production. Specifically, they determined KLF4’s pivotal role through its absence — that is, the mitochondria…