Science + Tech

A scientific team from Case Western Reserve University School of Medicine and Cleveland Clinic has developed a new way to identify second-line antibiotics that may be effective in killing germs already resistant to a first-line antibiotic – potentially helping overcome antibiotic resistance. This…

Zihua Gong, MD, PhD A new five-year, $1.8 million award will allow Zihua Gong, MD, PhD to work to better understand the mechanisms of resistance of PARP inhibitors (PARPi) that induce cell death in BRCA1 and BRCA2-deficient cancer cells associated with breast and ovarian cancer.…

Microscopic examination of brain tissues of prion-infected animals. (Left) Staining shows spongiform degeneration. (Right) Staining shows intense misfolded prion protein. Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease in…

CWRU, CSU initiative designed to shape region into digital innovation leader The Internet of Things Collaborative (IoTC), a partnership between Case Western Reserve and Cleveland State universities, is bringing together industrial, governmental, educational, neighborhood and nonprofit entities in…

The following is a message from Director Stan Gerson, MD and Associate Director for Basic Research Ruth Keri, PhD. The Case Comprehensive Cancer Center would like to thank Bingcheng Wang, PhD and Alex Almasan, PhD for their hard work in leading the Alex…

Monday is Martin Luther King Day in America. Though much has improved in our country for African Americans since his tragic assassination in 1968 – the year that so much changed – we still live in a world where serious health disparities persist, and we have too few tools to combat them. As Dr.…

Following evaluation of faculty-led proposals, the leadership of the University Hospitals (UH) Research Division has announced the establishment of their first two Centers of Excellence (COEs): the Center for Integrated and Novel Approaches in Vascular-Metabolic Disease (CINEMA) and the Center for…

Results in mouse sepsis model lay foundation for clinical trials Biochemists, microbiologists, drug discovery experts and infectious disease doctors have teamed up in a new study that shows antibiotics are not always necessary to cure sepsis in mice. Instead of killing causative bacteria with…

Bioethics of brain organoids to be explored by team led by CWRU researcher Insoo Hyun Research scientists around the world are now able to investigate the structural, cellular and developmental intricacies of the human brain using bioengineered stem cell-based models called organoids. But the…

We often cite our favorable mentions in the legendary Flexner report of 1910 as early evidence of our longstanding excellence in medical education. But do you know who Abraham Flexner was? A recent book by Robert Hromas, MD, dean of the School of Medicine at the University of Texas San Antonio,…