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Science + Tech

Cancer Innovation Pilot Awardees Announced
The Case Comprehensive Cancer Center (Case CCC) has made pilot award selections following a recent RFA. Selected projects were recognized as highly innovative and impactful, and likely to generate key data for larger, nationally competitive grants. Investigators were permitted to submit…
Researchers Uncover Novel Mechanism behind Schizophrenia
An international team of researchers led by a Case Western Reserve University School of Medicine scientist has uncovered a novel mechanism in which a protein—neuregulin 3—controls how key neurotransmitters are released in the brain during schizophrenia. The protein is elevated in people with…
Researchers Identify Dozens of New Gene Changes That Point to Elevated Risk of Prostate Cancer in Men of European Descent
As the result of a six-year long research process, Fredrick R. Schumacher, PhD, MPH, a cancer epidemiology researcher at Case Western Reserve University School of Medicine, and an international team of more than 100 colleagues have identified 63 new genetic variations that could indicate higher…
Attention Deficit Disorders Could Stem from Impaired Brain Coordination
WATCH VIDEO Researchers from Case Western Reserve University School of Medicine and colleagues have discovered how two brain regions work together to maintain attention, and how discordance between the regions could lead to attention deficit disorders, including schizophrenia, bipolar disorder,…
Pediatric Cancer Research at Case Western Reserve University and UH Rainbow Babies & Children’s Hospital Gets a Boost from St. Baldrick’s Foundation
Leading cancer researchers, Alex Huang MD, PhD, and Yamilet Huerta, MD have been awarded $186,405 in grants from the St. Baldrick’s Foundation to conduct pediatric cancer research. Huang, professor of pediatrics at Case Western Reserve University School of Medicine and co-leader of the…
Case Western Reserve Researcher and International Colleagues Identify Genetic Mutation Underlying Severe Childhood Brain Disorder
A comparison of an unaffected brain and an affected brain with pachygyria. Ashleigh Schaffer, PhD, assistant professor of genetics at Case Western Reserve University School of Medicine, and a team of global genetics experts have discovered a genetic mutation and the faulty development…
Big Data and Advanced Artificial Intelligence Techniques Used to Tackle Alzheimer’s Disease
"Our goal is to uncover more about the mechanism of Alzheimer’s and other diseases that involve memory loss and the breakdown of the neurological system." - Rong Xu, PhD     Sports concussions, Parkinson’s disease, and hormone therapy for cancer – all can have memory loss as symptoms.…
New Options for Breast Cancer Drug Development Found in Estrogen Receptors
human Estrogen Receptor alpha Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually develop drug resistance, leaving doctors desperate for…
Case Western Reserve’s Ahmad Khalil Receives NIH Funding to Develop New Paradigm in Fight against Colorectal Cancer
Ahmad Khalil, PhD Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding genes also contribute to the development and spreading…
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Case Western Reserve’s Ahmad Khalil receives NIH funding to develop new paradigm in fight against colorectal cancer
Targeting longnNoncoding RNAs may offer gains compared to conventional approaches Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding…