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Science + Tech

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Happy New Year
The holiday season is over … the wrapping paper that was strewn about the room has been collected and discarded; the lights unstrung and put away, the needles from the greens swept up. The New Year is upon us. It’s 2018. We are now in our 175th anniversary year. It will be August before we…
Zooming in on Protein to Prevent Kidney Stones
Researchers have applied Nobel prize-winning microscope technology to uncover an ion channel structure that could lead to new treatments for kidney stones. In a recent study published in Nature Structural and Molecular Biology, researchers revealed atomic-level details of the protein that serves as…
Fish Use Deafness Gene to Sense Water Motion
Fish sense water motion the same way humans sense sound, according to new research out of Case Western Reserve University School of Medicine. Researchers discovered a gene also found in humans helps zebrafish convert water motion into electrical impulses that are sent to the brain for perception.…
Selective Suppression of Inflammation Could Deplete HIV and Control HIV Activation
A class of anti-inflammatory drugs already FDA-approved for rheumatoid arthritis could “purge” the reservoir of infected immune cells in people infected by HIV, according to new research. When culturing cells from HIV-infected individuals, researchers found the medications tofacitinib and…
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Case Western Reserve research advance may prevent a form of hereditary hearing loss
Four-fold improvement in hearing for a mouse model of deafness A research advance co-led by Case Western Reserve University School of Medicine’s Kumar Alagramam may stop the progression of hearing loss and lead to significant preservation of hearing in people with Usher syndrome type III, a form…
Two Studies Find Stress Reprograms Cells
In a pair of publications, researchers have shown how cells adapt to stressors—like water loss—by reprogramming their internal signaling networks. The studies describe previously unknown mechanisms that cells use to send signals between cellular machinery and avoid cell death. According to the…
Researchers Find Possible Markers for Earlier Diagnosis of Aggressive Form of Tongue Cancer
Squamous cell carcinoma of the tongue, also known as oral tongue cancer, is an aggressive form of cancer that generally affects older people. Patients with the disease often find it difficult to eat, swallow food, or speak. Reasons for its generally poor prognosis include late detection, before…
New Research Aims to Improve the Lives of Children with High Grade Glioma
Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine has been awarded a $100,000 Josh Metzger Memorial Fox Trot Grant sponsored by the Prayers From Maria Foundation, in support of pediatric neurosurgical oncology research. Violette Recinos, MD, director of…
Points of Light
The winter solstice is upon us, and after that, the days will lengthen and light will return to the land.  Our winter season is marked by many holiday celebrations full of goodwill and light. It’s been a very successful year. Our talented students have produced another delightful Doc Opera. Our…
Researchers Repurpose Immune-Activating Cytokine to Fight Breast Cancer
The most lethal form of breast cancer could have a new treatment option, according to new research out of the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine. In the Proceedings of the National Academy of Sciences, researchers showed triple-negative breast…