Science + Tech

Researchers repurpose pain meds to kill cancer cells Researchers at the Case Comprehensive Cancer Center (CCCC) at Case Western Reserve University have helped develop a computer program to find new indications for old drugs. The computer program, called DrugPredict, matches existing data about…

Researchers from Case Western Reserve University School of Medicine and collaborators have received a five-year, $2.8 million grant from the National Institute on Aging to identify FDA-approved medications that could be repurposed to treat Alzheimer’s disease. The award enables the researchers to…

Donor tissue can be stored for 11 days before transplantation—four days longer than current convention New national research led by Jonathan Lass of Case Western Reserve University School of Medicine has found that corneal donor tissue can be safely stored for 11 days before transplantation…

The holiday season is over … the wrapping paper that was strewn about the room has been collected and discarded; the lights unstrung and put away, the needles from the greens swept up. The New Year is upon us. It’s 2018. We are now in our 175th anniversary year. It will be August before we…

Researchers have applied Nobel prize-winning microscope technology to uncover an ion channel structure that could lead to new treatments for kidney stones. In a recent study published in Nature Structural and Molecular Biology, researchers revealed atomic-level details of the protein that serves as…

Fish sense water motion the same way humans sense sound, according to new research out of Case Western Reserve University School of Medicine. Researchers discovered a gene also found in humans helps zebrafish convert water motion into electrical impulses that are sent to the brain for perception.…

A class of anti-inflammatory drugs already FDA-approved for rheumatoid arthritis could “purge” the reservoir of infected immune cells in people infected by HIV, according to new research. When culturing cells from HIV-infected individuals, researchers found the medications tofacitinib and…

Four-fold improvement in hearing for a mouse model of deafness A research advance co-led by Case Western Reserve University School of Medicine’s Kumar Alagramam may stop the progression of hearing loss and lead to significant preservation of hearing in people with Usher syndrome type III, a form…

In a pair of publications, researchers have shown how cells adapt to stressors—like water loss—by reprogramming their internal signaling networks. The studies describe previously unknown mechanisms that cells use to send signals between cellular machinery and avoid cell death. According to the…

Squamous cell carcinoma of the tongue, also known as oral tongue cancer, is an aggressive form of cancer that generally affects older people. Patients with the disease often find it difficult to eat, swallow food, or speak. Reasons for its generally poor prognosis include late detection, before…