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Alzheimer's disease

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Mandel School’s Ann Nguyen receives grant to study risk factors for Alzheimer’s disease and related dementias among older Black adults
Ann Nguyen, assistant professor at the Jack, Joseph and Morton Mandel School of Applied Social Sciences, received a new grant funded by the Research Centers Collaborative Network from a parent grant from the National Institute on Aging (NIH). This is a two-year grant, totaling $50,000. She is the pr...
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Why women may be more susceptible to Alzheimer’s disease
Case Western Reserve University School of Medicine researchers identify mechanism in brain tissue that may explain disparity between men and women Case Western Reserve University researchers have identified a mechanism in brain tissue that may explain why women are more vulnerable to Alzheimer’s di...
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5 things to know about… Alzheimer’s disease
When Jonathan Haines was learning about genetics in his high school biology class, he thought it was going to be pretty straightforward—you get one copy of genes from mom, one copy from dad and that’s it. “By the time I realized it was really complex, I was already hooked,” said Haines, the Mary W....
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Study identifies therapeutic target for Alzheimer’s disease, revealing strategy for preventing or slowing disease progression
Findings support restored memory function by as much as 50% About 11% of the U.S. population 65 and older has been diagnosed with Alzheimer’s disease (AD), the most common form of dementia that results in memory loss and cognitive impairment, according to the Alzheimer’s Association. And the World...
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Findings open the way to more precise diagnoses and treatments of Alzheimer’s disease
Case Western Reserve University-led research team discovers why some cases result in rapid decline and death An international team led by Case Western Reserve University School of Medicine has made a significant breakthrough in understanding why Alzheimer’s disease progresses so rapidly in some peo...
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National Institute on Aging awards $15.4 million to continue support for Cleveland Alzheimer’s Disease Research Center
Center is one of 31 NIH-funded centers in the nation The National Institute on Aging of the National Institutes of Health (NIH) has awarded a grant expected to total $15.4 million to continue funding the Cleveland Alzheimer’s Disease Research Center. The new five-year award will support the multi-i...
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Unraveling the origins of Alzheimer’s disease
Researchers find new hints that could explain how the disease spreads in human brains Case Western Reserve University researchers studying human prions—misfolded proteins that cause lethal and incurable diseases—have, for the first time, identified surface features responsible for the replication o...
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New Alzheimer's disease pathway discovered, providing earlier target for potential therapies
A novel Alzheimer’s disease marker—coming early in progression of the condition—could open significant new fronts of research into possible therapies Researchers at Case Western Reserve University School of Medicine have identified a new target in development of Alzheimer’s disease (AD) that could ...
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New School of Medicine study identifies novel mechanisms that cause protein clumping in Alzheimer’s and other degenerative brain diseases
A team of researchers at Case Western Reserve University School of Medicine has taken a major step toward understanding the mechanisms involved in the formation of large clumps of tau protein, a hallmark of Alzheimer’s disease and several other neurodegenerative disorders. Their findings may help t...
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Electronic health records used in study of drug-effectiveness to reduce risk of Alzheimer’s disease
Researchers have harnessed the power of electronic health records to gain insight into the potential of inflammation-controlling medications to reduce a patient’s Alzheimer’s disease risk. Rong Xu Rong Xu, professor of biomedical informatics and director of the Center for Artificial Intelligence i...