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Alzheimer's disease

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New School of Medicine study identifies novel mechanisms that cause protein clumping in Alzheimer’s and other degenerative brain diseases
A team of researchers at Case Western Reserve University School of Medicine has taken a major step toward understanding the mechanisms involved in the formation of large clumps of tau protein, a hallmark of Alzheimer’s disease and several other neurodegenerative disorders. Their findings may help…
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Electronic health records used in study of drug-effectiveness to reduce risk of Alzheimer’s disease
Researchers have harnessed the power of electronic health records to gain insight into the potential of inflammation-controlling medications to reduce a patient’s Alzheimer’s disease risk. Rong Xu Rong Xu, professor of biomedical informatics and director of the Center for Artificial Intelligence…
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Possible Alzheimer’s breakthrough suggested
Case Western Reserve University School of Medicine researchers say newly found protein is bio-marker for disease; suggest suppression of ‘aggregatin’ could lead to future treatments to slow Alzheimer’s progression Researchers at Case Western Reserve University School of Medicine say they have…
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Cleveland researchers recruiting for Alzheimer’s disease clinical trial
CWRU School of Medicine and UH Cleveland Medical Center study to measure the drug efavirenz’s potential improvement in people with early onset Alzheimer’s disease Case Western Reserve University School of Medicine and University Hospitals (UH) Cleveland Medical Center have enrolled their first…
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National Institute on Aging awards $4.23 million to establish Cleveland Alzheimer’s Disease Research Center
New center to be one of 31 NIH-funded centers in the nation The National Institute on Aging of the National Institutes of Health awarded a $4.23 million grant to establish the Cleveland Alzheimer’s Disease Research Center. The two-year award will support the development of a multi-institution…
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CWRU’s Jonathan Haines secures $14.6 million grant to study Alzheimer’s disease across diverse populations
Alzheimer’s disease symptoms, such as memory loss or cognitive decline, can present in different ways among people with diverse ethnic backgrounds. Researchers know a complex mix of social, behavioral and genetic variables can impact the onset and progression of this disease. Recent studies show…
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Big data and advanced artificial intelligence techniques used to tackle Alzheimer’s disease
CWRU’s Rong Xu receives $5 million in funding from NIH’s National Institute on Aging Sports concussions, Parkinson’s disease and hormone therapy for cancer all can have memory loss as symptoms. But can the biochemical processes of each reveal anything about the memory loss associated with…
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Probing Alzheimer’s at both ends of the spectrum
Researchers receive NIH grants to study Amish resilience and rapid onset Researchers from Case Western Reserve University School of Medicine have received two grant awards, in partnership with investigators from other institutions, from the National Institutes of Health to conduct major studies on…
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New machine-learning program shows promise for early Alzheimer’s diagnosis
A new machine-learning program developed by researchers at Case Western Reserve University appears to outperform other methods for diagnosing Alzheimer’s disease before symptoms begin to interfere with everyday living, initial testing shows. More than 5 million Americans may have Alzheimer’s…