Alzheimer's disease

Case Western Reserve University-led research team discovers why some cases result in rapid decline and death An international team led by Case Western Reserve University School of Medicine has made a significant breakthrough in understanding why Alzheimer’s disease progresses so rapidly in some…

Center is one of 31 NIH-funded centers in the nation The National Institute on Aging of the National Institutes of Health (NIH) has awarded a grant expected to total $15.4 million to continue funding the Cleveland Alzheimer’s Disease Research Center. The new five-year award will support the…

Researchers find new hints that could explain how the disease spreads in human brains Case Western Reserve University researchers studying human prions—misfolded proteins that cause lethal and incurable diseases—have, for the first time, identified surface features responsible for the replication…

A novel Alzheimer’s disease marker—coming early in progression of the condition—could open significant new fronts of research into possible therapies Researchers at Case Western Reserve University School of Medicine have identified a new target in development of Alzheimer’s disease (AD) that could…

A team of researchers at Case Western Reserve University School of Medicine has taken a major step toward understanding the mechanisms involved in the formation of large clumps of tau protein, a hallmark of Alzheimer’s disease and several other neurodegenerative disorders. Their findings may help…

Researchers have harnessed the power of electronic health records to gain insight into the potential of inflammation-controlling medications to reduce a patient’s Alzheimer’s disease risk. Rong Xu Rong Xu, professor of biomedical informatics and director of the Center for Artificial Intelligence…

Case Western Reserve University School of Medicine researchers say newly found protein is bio-marker for disease; suggest suppression of ‘aggregatin’ could lead to future treatments to slow Alzheimer’s progression Researchers at Case Western Reserve University School of Medicine say they have…

CWRU School of Medicine and UH Cleveland Medical Center study to measure the drug efavirenz’s potential improvement in people with early onset Alzheimer’s disease Case Western Reserve University School of Medicine and University Hospitals (UH) Cleveland Medical Center have enrolled their first…

New center to be one of 31 NIH-funded centers in the nation The National Institute on Aging of the National Institutes of Health awarded a $4.23 million grant to establish the Cleveland Alzheimer’s Disease Research Center. The two-year award will support the development of a multi-institution…

Alzheimer’s disease symptoms, such as memory loss or cognitive decline, can present in different ways among people with diverse ethnic backgrounds. Researchers know a complex mix of social, behavioral and genetic variables can impact the onset and progression of this disease. Recent studies show…