Case Comprehensive Cancer Center

Invited commentary by Drs. Paula Silverman and Cheryl Thompson  A recent study by Jones et al. in The British Journal of Cancer (BJC)(Jones ME. Br J Cancer. 2016 Aug 23) estimated an almost 3 fold (2.74 times) increase risk of breast cancer among post-menopausal women who used combination estrogen…

15 gene mutations lead to higher recurrence and metastasis; genes may contribute to lower survival rates seen in African-Americans Case Comprehensive Cancer Center researchers, a research collaboration which includes University Hospitals Seidman Cancer Center and Case Western Reserve University,…

Case Comprehensive Cancer Center researchers identify several structurally abnormal genes in esophageal adenocarcinoma in first ever genome-wide search Despite years of research, cellular mechanisms contributing to cancers like esophageal adenocarcinoma have remained elusive. What has puzzled…

This past week attended the national meeting of the Association of American Cancer Institutes (AACI) in Chicago. It was an excellent meeting of cancer center directors and administrators that included discussion of implementation of genomic tumor boards, use of molecular testing in clinical…

When Monica Webb Hooper saw a Facebook post about an opening to establish and direct the Office of Cancer Disparities Research at Case Western Reserve University, she knew it had her name written all over it. She didn’t know much about Cleveland, but when she came here from the University of Miami…

Findings confirmed in patient biopsies and laboratory models A team of Case Comprehensive Cancer Center researchers has uncovered one way certain tumors resist vital medication. In the study published in Oncotarget (Merry CR. Oncotarget. 2016 Jul 16), the researchers studied tumor biopsies…

7 am Saturday morning saw the 100 and 200+ mile Velosano bikers head off with the cheers of friends and leaders - I saw Brian Bolwell safely behind the roadside barrier smiling, arms raised. The day was perfect for riders - cool, with a short thunderstorm on the way in and a relaxing scenic route…

Stanton L. Gerson, director of the Case Comprehensive Cancer Center, wrote a guest column for The Plain Dealer about Vice President Joe Biden’s Cancer Moonshot. His column, titled “Cleveland matters for Vice President Biden's Cancer Moonshot,” detailed how teams in Cleveland have worked with the…

Changes in benign tissues next to prostate tumors may provide an early warning for patients at higher risk for biochemical recurrence after a radical prostatectomy, a study by researchers at Case Western Reserve University and Johns Hopkins Medical Institutions shows. Biochemical recurrence, which…

Message from the Associate Director: Brian Bolwell, MD Thomas Donohue, President and CEO, US Chamber of Commerce, hosted a Cancer Moonshot Breakfast Panel in downtown Cleveland last Wednesday. I participated in the panel, along with Toby Cosgrove, MD, President and CEO of Cleveland Clinic, Louis…