genetics

Benjamin Clayton, assistant professor of genetics and genome sciences at Case Western Reserve University School of Medicine, was recognized as a recipient of the End Alexander Disease Foundation’s (End AxD) inaugural 2025 Grant Program. Grants typically range from $50,000 to $100,000 in direct…

Advanced computer analysis unlocks cellular secrets

Earlier this month, Case Western Reserve University School of Medicine’s Rania Ziar, a PhD student, and advisor Paul Tesar, professor in the Department of Genetics and Genome Sciences, were named to the HHMI Gilliam Fellows Program 2025 cohort. This program—which supports graduate students and…

Age-related macular degeneration (AMD), which affects about 200 million people worldwide and can result in legal blindness, impairs an area of the eye (retina) used for reading, driving and many other critical daily tasks. A new study of large existing patient datasets indicates genetic and…

When Dean Stan Gerson called Paul Tesar to the stage at the School of Medicine’s State of the School address last month, the Dr. Donald and Ruth Weber Goodman Professor of Innovative Therapeutics believed he’d be speaking about the Institute of Glial Sciences—a new center he’s directing. Instead,…

Irregularities in the body’s genetic coding to make proteins are linked to cancerous tumors. But most genetic material contains elements whose function isn’t clear. Could abnormalities in non-coding material also impact a person’s health, or even be linked to cancers as well? A new study by…

When Jonathan Haines was learning about genetics in his high school biology class, he thought it was going to be pretty straightforward—you get one copy of genes from mom, one copy from dad and that’s it. “By the time I realized it was really complex, I was already hooked,” said Haines, the Mary…

Case Western Reserve University researchers combine novel chemical method with CRISPR gene-editing tools to target disease-specific versions of genetic code The gene-editing technique known as CRISPR accelerated biological and medical research in the last decade by allowing scientists to repair…

In a ceremony Oct. 22, School of Medicine Dean Stan Gerson awarded Maria Hatzoglou the Case Medal for Excellence in Health Science Innovation. She was recognized with the highest honor bestowed by the school for her groundbreaking research, decades of service and for being a wonderful role model.…

In 2018, eight years after starting his lab, Paul Tesar was formally asked about his mentoring philosophy for the first time. He’d been nominated for a mentorship award and, as a finalist, had to answer questions about his mentorship style and strategy. The problem was Tesar never spent time…