genetics

There are treatments, but no cures, for millions of people worldwide suffering from diseases such as multiple sclerosis, cerebral palsy and leukodystrophies (rare genetic diseases that affect the brain and spinal cord). This is why Paul Tesar and his lab continue to conduct promising translational r...

A research article co-authored by Anna Mitchell, associate professor in the Department of Genetics and Genome Sciences, and Michiko Watanabe, professor of pediatrics, has been published in Birth Defects Research. Mitchell’s and Watanabe’s article is part of a special issue of Birth Defects Researc...

Case Western Reserve University researchers use lipids to safely deliver gene therapy to the eye, successfully holding off advance of rare, inherited eye disorder Researchers at Case Western Reserve University have used a unique method to safely deliver gene therapy to fight a rare, but irreversibl...

Now enrolling for a research study: Healthy contact lens wearers (who have been using contacts for at least five years) in the age range of 15-70 and are of European ancestry (Causasian) and have no history of a corneal ulcer from contact lenses. The research study involves: Brief eye examAnswer ...

Technique improves understanding of myelin disease; expands ability to screen potential therapies for rare pediatric brain disorder In two recently published papers, a scientific team at Case Western Reserve University School of Medicine reports on the discovery and implementation of a new, more eff...

Targeting longnNoncoding RNAs may offer gains compared to conventional approaches Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding ge...

Ahmad Khalil, assistant professor of genetics and biochemistry and member of the Case Comprehensive Cancer Center, will serve as a session organizer for the American Kavli Frontiers of Science symposium Oct. 19-21 in Nanjing, China. The symposium is a joint effort of the Chinese Academy of Sciences...

Anthony Wynshaw-Boris can’t recall a time when he didn’t know he would have a career in medicine. It was just something he feels like he was “almost born with”—fitting for researcher who would go on to study genetics. With a career at the intersection of pediatrics and genetics, Wynshaw-Boris, the ...

Researchers generate missing cell type in brain “organoids” A cutting-edge laboratory technique that turns human stem cells into brain-like tissue now recapitulates human brain development more accurately than ever, according to a new study from Case Western Reserve University School of Medicine. Th...

CWRU researchers take step closer to uncovering new genetic causes of infertility Scientists have found distinctive portions of genetic material—known as lncRNAs—that help sperm develop. A study published in Biology of Reproduction found male mice lacking a particular lncRNA have low sperm count, su...