News Releases

"Our goal is to uncover more about the mechanism of Alzheimer’s and other diseases that involve memory loss and the breakdown of the neurological system." - Rong Xu, PhD Sports concussions, Parkinson’s disease, and hormone therapy for cancer – all can have memory loss as symptoms. B...

human Estrogen Receptor alpha Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually develop drug resistance, leaving doctors desperate for alterna...

Ahmad Khalil, PhD Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding genes also contribute to the development and spreading ...

Alex Huang, MD, PhD Leading cancer researcher, Alex Huang MD, PhD, has been awarded a three-year, $1.35 million grant from the St. Baldrick’s Foundation and the Osteosarcoma Collaborative to develop new ways to treat osteosarcoma, a rare cancer that begins in the bone. Huang, who is a pr...

Researchers from Case Western Reserve University School of Medicine have shown that a single “cocktail” of three pill-based anti-parasite medications is significantly more effective at killing microscopic larval worms in people diagnosed with lymphatic filariasis, commonly known as elephantiasis, th...

Mukesh Jain, MD, and colleagues have been awarded a five-year, $6M grant from the Paris-based Fondation Leducq to conduct a thorough analysis of the pivotal role of KLF2 in vascular-related functions and disorders. The team’s grant was one of five awarded globally and aims to improve knowledge and t...

Lin Mei, MD, PhD, joins Case Western Reserve University School of Medicine as professor, chair of the Department of Neurosciences, and director of the Cleveland Brain Health Initiative. Mei comes to the medical school following 13 highly productive years at Medical College of Georgia at Augusta Univ...

Mark Jackson, PhD Case Western Reserve University School of Medicine is preparing and inspiring a new generation of cancer investigators through Cancer-focused Summer Undergraduate Research (CanSUR). The 10-week program recently received a five-year National Institutes of Health (National...

Serotonin-induced activation of serotonin (3A) receptors Serotonin (3A) receptors are common drug targets in the treatment of pain, gastrointestinal dysfunctions, and mood disorders yet little is known about their three-dimensional structure. Details about serotonin receptor structures co...

Tissue from a mouse that has a functional Dazl gene, with fluorescent-labeled germ cells (left), and tissue from a mouse lacking the Dazl gene (right). A single protein regulates a battery of key genes inside developing sperm, according to a new study out of Case Western Reserve Universit...