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New Skin Test Detects Prion Infection Before Symptoms Appear
Microscopic examination of brain tissues of prion-infected animals. (Left) Staining shows spongiform degeneration. (Right) Staining shows intense misfolded prion protein. Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease in cattl...
Case Western Reserve’s John “Chip” Tilton, MD, Secures School of Medicine’s Fourth Falk Catalyst Award
John “Chip” Tilton, MD, of Case Western Reserve University School of Medicine will receive $300,000 from the Dr. Ralph and Marian Falk Medical Research Trust to develop a virus-based “nanoPOD” (nanoscale PrOtein Delivery) platform to help treat rare genetic diseases. Tilton is associate professor an...
Case Western Reserve/UH Launch Bipolar CHOICE Trial Site
CLEVELAND - The Mood Disorders Program at Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, along with the Bipolar Trials Network, is launching Bipolar CHOICE (Clinical Health Outcomes Initiative in Comparative Effectiveness). The 10-site nationwide tri...
International TB Campaign Launches on World TB Day
CLEVELAND - Physicians across the globe are coming together to advocate for a large, underrepresented patient population – those suffering from tuberculosis (TB). On World TB Day, March 24th, a team of physician and researchers led by Case Western Reserve University School of Medicine’s Tuberculosis...
Breakthrough Discovery Unveils “Master Switches” in Colon Cancer
CLEVELAND - A team of researchers at Case Western Reserve University School of Medicine have identified a new mechanism by which colon cancer develops. By focusing on segments of DNA located between genes, or so-called “junk DNA,” the team has discovered a set of master switches, i.e., gene enhancer...
A toxic byproduct of hemoglobin could provide clues for possible treatments for cerebral hemorrhage and Creutzfeldt-Jakob Disease
Scientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to stroke and a variety of neurodegenerative conditions, including sporadic Creutzfeldt-Jakob disease, Alzheimer’s disease, and Parkinson’s disea...
Researchers Uncover Novel Mechanism behind Schizophrenia
An international team of researchers led by a Case Western Reserve University School of Medicine scientist has uncovered a novel mechanism in which a protein—neuregulin 3—controls how key neurotransmitters are released in the brain during schizophrenia. The protein is elevated in people with schizop...
Attention Deficit Disorders Could Stem from Impaired Brain Coordination
WATCH VIDEO Researchers from Case Western Reserve University School of Medicine and colleagues have discovered how two brain regions work together to maintain attention, and how discordance between the regions could lead to attention deficit disorders, including schizophrenia, bipolar disorder, and...
Pediatric Cancer Research at Case Western Reserve University and UH Rainbow Babies & Children’s Hospital Gets a Boost from St. Baldrick’s Foundation
Leading cancer researchers, Alex Huang MD, PhD, and Yamilet Huerta, MD have been awarded $186,405 in grants from the St. Baldrick’s Foundation to conduct pediatric cancer research. Huang, professor of pediatrics at Case Western Reserve University School of Medicine and co-leader of the Hematopoieti...
Researchers Identify Dozens of New Gene Changes That Point to Elevated Risk of Prostate Cancer in Men of European Descent
As the result of a six-year long research process, Fredrick R. Schumacher, PhD, MPH, a cancer epidemiology researcher at Case Western Reserve University School of Medicine, and an international team of more than 100 colleagues have identified 63 new genetic variations that could indicate higher risk...