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April 10, 2015
Professor Jonathan Stamler’s latest findings regarding nitric oxide have the potential to reshape fundamentally the way we think about the respiratory system – and offer new avenues to save lives. It may be time to rewrite the textbooks. Scientific dogma has the respiration process involving only…
April 03, 2015
After discovering a unique group of people resistant to tuberculosis (TB) infection, Case Western Reserve researchers are leading an international team dedicated to understanding exactly how they fight off a disease that claims 1.5 million lives each year. The team’s goal is to use lessons…
March 23, 2015
The concept was simple: If two compounds each individually show promise in preventing colon cancer, surely it’s worth trying the two together to see if even greater impact is possible. In this instance, Case Western Reserve cancer researcher Li Li, MD, PhD, could not have been more prescient. Not…
March 23, 2015
A surgical sedative may hold the key to reversing the devastating symptoms of a neurodevelopmental disorder found almost exclusively in females. Ketamine, used primarily for operative procedures, has shown such promise in mouse models that Case Western Reserve and Cleveland Clinic researchers soon…
March 19, 2015
Half a century ago, a concentrated global effort nearly wiped a disfiguring tropical disease from the face of the earth. Now, says Case Western Reserve’s James W. Kazura, MD, it’s time to complete the work. In a perspective column in the Feb.19 New England Journal of Medicine, Kazura responded to…
March 13, 2015
Case Western Reserve researchers are part of an international team that has discovered that a common herpes drug reduces HIV-1 levels — even when patients do not have herpes. Published online in Clinical Infectious Diseases, the finding rebuts earlier scientific assumptions that Valacyclovir…
March 12, 2015
Case Western Reserve scientists have discovered that speed matters when it comes to how messenger RNA (mRNA) deciphers critical information within the genetic code — the complex chain of instructions critical to sustaining life. The investigators’ findings, which appear in the March 12…
February 09, 2015
A researcher at Case Western Reserve University School of Medicine has been awarded $3.9 million to determine if the combination of the human immunodeficiency virus (HIV) and drug abuse is a double kick in the gut, leading to organ damage throughout the body. Alan D. Levine, PhD, a professor of…
February 02, 2015
Case Western Reserve’s chemical compound aimed at restoring spinal cord function may have an additional purpose: stopping potentially fatal arrhythmias after heart attack. Case Western Reserve neurosciences professor Jerry Silver, PhD, long has believed that lessons learned over decades from…
January 21, 2015
Case Western Reserve scientists have taken a huge leap toward identifying root causes of psoriasis, an inflammatory skin condition affecting 125 million people around the world. Of the roughly 50,000 proteins in the human body, researchers have zeroed in on four that appear most likely to…