For a multicontact cuff electrode to be functional all target
fascicles must be accessible. This can be achieved if there
are sufficient numbers of contact to cover all possible positions
of nerves inside a cuff ofr techniques must be developed
to create steerable excitation sites. The development of
techniques to steer (or move a virtual excitation sites)
would make it possible to manufacture functional multicontact
cuff type electrodes with fewer contacts, leads and simpler
connectors. In the following section we show that “field
steering” can be use to position an excitation site
(a virtual excitation site) at a point in space where there
is no actual contact in the cuff electrode.
Anodic
Steering:
A comparison was made of the torque outputs produced by
direct stimulation of each branch of the sciatic Sciatic
nerve, labeled as Tib, MG, LG and CP, and to the torque produced
by stimulation of each contact in the cuff electrode, labeled
0°, 90°, 180° and 270°, in Cat #388thea feline.
Based on the torque outputs, the Tib, MG, and LG branches
of the sciatic were activated by the 0°, 90°, and
180° contacts on the sciatic nerve. No single contact
activated the common peroneal by itself. The addition of
anodic steering current from the 0° position to the 270° position
(labeled c270°a0°) was found to produce the same
torque output as is was produced by stimulation of the common
peroneal branch. The inset in the bottom right corner is
a reconstruction of the nerve cross section and the relative
locations of each contact. A schematic of the configuration
used to apply current for the multiple contact stimulation
is also shown.
Cathodic Steering:
In
this experiment, no single contact activated the Medial Gastrocnemius
(MG MG) by itself. The addition of cathodic steering current
from the 90° position to the 180° position (labeled
c90°c180°) was found to activate the MG selectively
over its entire range. The inset in the top left corner is
a reconstruction of the nerve cross-section and the relative
locations of each contact. This schematic depicts the current
configuration used to apply the steering currents.
Summary
Shown
in this table are the stimulation combinations used at the
level of the sciatic nerve to achieve the same torque output
as each corresponding fascicle for each experiment are shown
in this table. For
In each case in which the same torque output as the corresponding
nerve branch was achieved, four placeholders were entered
to represent how the four corresponding contacts (0°,
90°, 180° and 270°) were used.
An open circle (o) represents a contact that was not used for that particular
configuration.
A minus sign (-) indicates that the corresponding contact was pulsed in the cathodic
direction.
A plus sign (+) indicates that the corresponding contact was pulsed in the anodic
direction.
Four filled circles (• • • •) indicate that the particular
torque was not achieved fully with single contact stimulation but not targeted
using steering currents due to time limitations. In no case was a particular
torque not achieved when multiple contact stimulation was attempted. The shaded
cells are the cases in which “collision block addition” was used
to verify the corresponding fascicle was fully and selectively activated.
The results of these experiments indicate that a four contact, self-sizing, cuff
electrode can be used to target activation of any one of four motor fascicles,
over it entire range, provided the stimulator is capable of effecting “field
steering” by the application of positive or negative currents to any of
the four contacts on demand and simultaneously.
Tarler, M. D. and J. Thomas Mortimer (2003) Selective and
independent activation of four motor fascicles using a four
contact nerve cuff electrode. IEEE Trans. In Press