Neural Damage

Results from an experiment from chronic stimulation are shown in this figure. A schematic of electrode placement is shown on the upper right.
The degree of damage to the neural tissues was classed into four grades. Level of damage from two pulse types, lead and lag, are shown below, plotted against the charge density and the charge.

o Pudenz et al. (1975) Surg. Neurol., vol 4, pp 389-400.

A model relating current, pulse phase and contact size was developed. Maximum current amplitude, maximum charge per phase, and maximum charge density per phase is shown in the figure against electrode perimeter and electrode area. A parameter ‘k’ was derived from the fit model.

Shannon (1992) IEEE Trans. BME, vol 39, p 424-426.