David L. Wilson, PhD

Robert J. Herbold Professor of Biomedical Engineering
Department of Biomedical Engineering
Case School of Engineering
Department of Radiology
School of Medicine
Cancer Imaging Program
Case Comprehensive Cancer Center

Research Information

Research Interests

  • Image analysis and prediction using machine/deep learning

  • Cardiovascular imaging, particularly CT and intravascular optical coherence tomography imaging

  • Ophthalmological imaging

  • Cellular and molecular imaging

  • Advanced section-and-image microscopy approaches including cryo-imaging and 3D-MUSE suitable for large volumes of interest, including a whole mouse or organ


View All Publications

  1. Hao Wu, Brendan L. Eck, Jacob Levi, Anas Fares, Yuemeng Li, Di Wen, Hiram G. Bezerra, Raymond F. Muzic, Jr., and David L. Wilson, “SLICR super-voxel algorithm for fast, robust quantification of myocardial blood flow by dynamic computed tomography myocardial perfusion imaging,” J. Med. Imaging, vol. 6, no. 4, p. 046001, Nov. 2019. PMCID: PMC6833456

  2. Jacob Levi, Brendan L. Eck, Rachid Fahmi, Hao Wu,Mani Vembar, Amar Dhanantwari, Anas Fares, Hiram G. Bezerra, and David L. Wilson. “Comparison of Automated Beam Hardening Correction (ABHC) Algorithms.” Medical Physics (2020). Available online prior to publication.

  3. Lee J, Gharaibeh Y, Kolluru C, Zimin VN, Dallan LAP, Kim JN, Bezerra HG, and Wilson DL, Segmentation of coronary calcified plaque in intravascular OCT images using a two-step deep learning approach, IEEE Access, 8, 225581-225593, 2020.

  4. Lee J, Prabhu D, Kolluru C, Gharaibeh Y, Zimin VN, Dallan LAP, Bezerra HG, and Wilson DL, Fully automated plaque characterization in intravascular OCT images using hybrid convolutional and lumen morphology features, Nature – Scientific Reports, 10(1), 2596, 2020.

  5. Zhou, Z., Qutaish, M., Han, Z., Schur, R. M., Liu, Y., Wilson, D. L., & Lu, Z. R. (2015). MRI detection of breast cancer micrometastases with a fibronectin-targeting contrast agent. Nature communications, 6, 2015.


Doctor of Philosophy
Electrical Engineering
Rice University
Master of Science
Biomedical Engineering
Penn State University
Bachelor of Science
West Virginia University