Xin Yu, ScD

Department of Biomedical Engineering
Case School of Engineering
School of Medicine
Department of Physiology and Biophysics
School of Medicine
Associate Professor
Department of Radiology
School of Medicine

Research Information

Research Interests

  • Magnetic resonance imaging and spectroscopy
  • In vivo metabolic imaging in diabetes and stroke
  • Magnetic resonance fingerprinting in pre-clinical studies

My laboratory is devoted to the development of magnetic resonance imaging (MRI) and spectroscopy (MRS) methods for integrative understanding of cardiovascular physiology and diseases. We aim to apply these techniques to elucidate the structure-function and energy-function relationships in diseased hearts. We are interested in both basic science and translational clinical research that combines the state-of-the-art NMR technology with molecular biology approaches to explore the mechanisms of myocardial remodeling in diseased hearts. Currently, we are investigating the myocardial remodeling processes in genetically manipulated mouse models, muscular dystrophy and diabetes in particular.

Awards and Honors

Research Award
Case Western Reserve University School of Engineering
Clement Vaturi Fellowship in Biomedical Engineering
Massachusetts Institute of Technology
Clement Vaturi Fellowship in Biomedical Engineering
Massachusetts Institute of Technology
Wolkman Fellowship of W.G.C. Whiting School of Engineering
The Johns Hopkins University
Wolkman Fellowship of W.G.C. Whiting School of Engineering
The Johns Hopkins University
American Institute for Medical and Biological Engineering (AIMBE)

Professional Memberships

International Society of Magnetic Resonance in Medicine
American Association for the Advancement of Science
American Heart Association
American Diabetes Association
International Society of Cerebral Blood Flow and Metabolism


View All Publications

Y Gu; C Wang; C Anderson; Y Liu; H Hu; ML Johansen; D Ma; Y Jiang; C Ramos-Estebanez; S Brady-Kalnay; MA Griswold; CA Flask; X Yu. Fast magnetic resonance fingerprinting for dynamic contrast-enhanced studies in mice. Magn Reson Med., Epub ahead of print, 2018. PMID: 29744935.

CY Wang; Y Liu; S Huang; MA Griswold; N Seiberlich; X Yu. 31P magnetic resonance fingerprinting for rapid quantification of creatine kinase reaction rate in vivo. NMR in Biomed., 30:e3786, 2017. PMID: 28915341.

Y Liu; Y Zhang; C Wu; J Zhu; C Wang; N Tomko; MD Linetsky; RG Salomon; C Ramos-Estebanez; Y Wang; X Yu. High resolution dynamic oxygen-17 MR imaging of mouse brain with golden-ratio-based radial sampling and k-space-weighted image reconstruction. Magn Reson Med., 79:256-263, 2018. PMID: 28295552.


Doctor of Science
Radiological Sciences,
Harvard-MIT Division of Health Sciences and Technology
Master of Science
Electrical Engineering
The Johns Hopkins University
Bachelor of Science
Electrical Engineering
University of Science and Technology, Hefei, Anhui, China

Residencies, Internships and Fellowships

Post-Doctoral Fellowship
Duke University