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Patent-Pending Probiotic Could Disrupt Crohn’s Disease Biofilms
Probiotics typically aim to rebalance bacteria populations in the gut, but new research suggests they may also help break apart stubborn biofilms. Biofilms are living microbial communities—they provide a haven for microbes and are often resistant to antibiotics. A new study describes a specific prob...
Medical Students Meet their “Match” when the Clock Strikes Noon
Today at noon, medical students–including those from Case Western Reserve School of Medicine and its Cleveland Clinic Lerner College of Medicine–opened envelopes to discover where their journey will take them for the next three to seven years as resident physicians. The National Residency Matching ...
Case Western Reserve University School of Medicine Ranked No. 1 in Ohio, and No. 24 nationally, by U.S. News & World Report
Case Western Reserve University School of Medicine has been named the No. 1 research-oriented medical school in Ohio, according to the influential annual ranking by U.S. News & World Report. In addition, the school was ranked one of the leading medical schools in America—at number 24. “All of us at...
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New Findings Shed Light on Origin of Upright Walking in Human Ancestors
Fossil hominin talus The oldest distinguishing feature between humans and our ape cousins is our ability to walk on two legs – a trait known as bipedalism. Among mammals, only humans and our ancestors perform this atypical balancing act. New research led by a Case Western Reserve Universi...
Health Insurance is not Assurance of Healthcare
CLEVELAND, February 27, 2019—Because of high out-of-pocket expenses, Ohioans who purchase subsidized health-exchange insurance often can't afford the care they need when they need it. That is a central finding of a new study from researchers at Case Western Reserve University School of Medicine. Ex...
Newly Identified Drug Targets Could Open Door for Esophageal Cancer Therapeutics
Gastroenterology Graphical abstract of TGF-beta pathway activity during progression of esophageal adenocarcinoma Blocking two molecular pathways that send signals inside cancer cells could stave off esophageal adenocarcinoma (EAC), the most common esophageal malignancy ...
Preventing “Cell Wall Remodeling” May Hold Key to Defeating Intransigent Superbugs in Cystic Fibrosis, Other Diseases
B. multivorans is a notorious pathogen that can cause infections such as pneumonia in immune-compromised individuals with underlying lung diseases, including cystic fibrosis. This pathogen can also cause rapid clinical deterioration in patients, including blood stream infections, which can lead to d...
Case Western Reserve Researcher Awarded $1.3 Million to Develop Decision-Making Tool for Treating Intimate Partner Violence
Case Western Reserve University School of Medicine’s Gunnur Karakurt, PhD has been awarded a four-year, $1.3 million grant from the National Institutes of Health to identify effective treatments for intimate partner violence (IPV), and to develop a decision-making tool for care providers. The projec...
Blood Cells Could Hold Master Clock Behind Aging
Blood cells could hold the key to aging, according to new research out of Case Western Reserve University School of Medicine. In a study published in Aging Cell, researchers found human blood cells have an intrinsic clock that remains steady even after transplant. The researchers say the clock could...
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Researchers Develop New Approach for Vanquishing Superbugs
A scientific team from Case Western Reserve University School of Medicine and Cleveland Clinic has developed a new way to identify second-line antibiotics that may be effective in killing germs already resistant to a first-line antibiotic – potentially helping overcome antibiotic resistance. This ne...